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Updated: Sep 15, 2025

Exploring Sequence Space to Identify Binding Sites for Regulatory RNA-Binding Proteins
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Exploring Sequence Space to Identify Binding Sites for Regulatory RNA-Binding Proteins

Published on: August 9, 2019

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对RNA结合蛋白的综合性分析确定DDX55是3'UTR异型多样性的新型调节者

Matthew R Gazzara1,2,3, Timothy Cater1,4, Michael J Mallory1

  • 1Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, PA, 19104, USA.

bioRxiv : the preprint server for biology
|July 14, 2025
PubMed
概括

研究人员确定了新型RNA结合蛋白 (RBPs),通过替代多基化 (APA) 调节信使RNA3'未翻译区域 (3'UTRs). 死亡盒RNA螺旋酶DDX55被验证为一种新的APA调节剂,特别影响具有RNA二级结构的多基化位点.

关键词:
3 UTR 其他替代性的多基解.在DDX55DDX55DDX55DDX55DDX55DDX55DDX55DDX55DDX关于RNA的规则是RNA规则.

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