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Tumor Transplantation for Assessing the Dynamics of Tumor-Infiltrating CD8+ T Cells in Mice
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内氨基酸缺乏症限制了CD8+ T细胞效应体的功能

Yan-Ting Chen1,2, Ya-Hui Lin2, Jahan Rahman2,3

  • 1Louis V. Gerstner Jr. Graduate School of Biomedical Sciences, New York, NY, USA.

bioRxiv : the preprint server for biology
|July 14, 2025
PubMed
概括

瘤微环境的氨基酸水平限制了CD8+T细胞蛋白质的合成和功能. 恢复氨基酸可用性可以增强T细胞效应器功能和抗瘤免疫力.

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