相关实验视频

Updated: Sep 15, 2025

Comparison of Predictive Performance of Three Lymph Node Staging Systems in Colorectal Signet Ring Cell Carcinoma Based on Machine Learning Model

Comparison of Predictive Performance of Three Lymph Node Staging Systems in Colorectal Signet Ring Cell Carcinoma Based on Machine Learning Model

Published on: April 18, 2025

中心静脉接入装置的癌症患者中CRT风险的预测模型:系统性审查和元分析

Wenjuan Yang¹, Meng Fang², Kangqin Cai¹

¹Department of Nephrology, Zigong First People's Hospital, Zigong, Sichuan, China.

Frontiers in medicine

|July 14, 2025

概括

使用中央静脉接入装置 (CVAD) 的癌症患者面临着与导管相关的血栓形成 (CRT) 的高风险. 本次审查评估了CVAD CRT现有的风险预测模型,发现大多数尽管存在高偏差风险,但表现中等至良好.

科学领域:

在瘤学瘤学.
血液学血液学血液学
医疗信息学医疗信息学

背景情况:

中心静脉接入装置 (CVAD) 在癌症患者中很常见.
导管相关血栓塞 (CRT) 是一个重要的并发症,在这个人群中发病率很高.
早期检测和风险评估对于有效的血栓预防至关重要.

研究的目的:

系统地审查和评估癌症患者中CVAD相关的血栓形成风险预测模型.
在这些模型中评估绩效并确定关键预测因素.

主要方法:

在多个数据库 (PubMed,Embase,Web of Science等) 进行全面的文献搜索. 在2024年5月之前.
使用预测模型偏差风险评估工具 (PROBAST) 进行独立选,数据提取和质量评估.
用于模型验证的曲线下面积 (AUC) 值的元分析.

主要成果:

十九篇论文确定了29个预测模型;报告的AUC值在0.470到1.000之间.
常见的预测因素包括D-二次体水平,BMI和糖尿病.
六个验证模型的AUC组合值为0.81,表明了良好的歧视,尽管所有研究都有高偏差风险.

结论:

现有的CRT预测模型显示预测性能中等至良好.
在所有纳入的研究中都注意到存在重大偏差风险,主要是由于报告的限制.
未来的研究需要方法严格,多中心验证和潜在的新模型的开发.

关键词:

癌症患者癌症患者导管相关的血栓形成 (CRT)中心静脉接入装置的使用.这是一个元分析.风险预测模型的风险预测模型

更多相关视频

Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery

Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery

Published on: September 27, 2024

Author Spotlight: Advancing Cancer Associated Thrombosis Research in Rodent Models

Author Spotlight: Advancing Cancer Associated Thrombosis Research in Rodent Models

Published on: January 5, 2024

相关概念视频

Venous Thrombosis III: Interprofessional Care

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...

Continuous Renal Replacement Therapy

Continuous Renal Replacement Therapy

Continuous Renal Replacement Therapy, also known as CRRT, is a procedural treatment for acute kidney injury (AKI) that gradually removes uremic toxins and fluids while maintaining acid-base balance and stabilizing electrolytes. It is particularly useful for hemodynamically unstable patients. Unlike intermittent hemodialysis, which is faster, CRRT provides a gentler approach over 24 hours, closely mimicking the function of natural kidneys. However, CRRT is not ideal for patients with...