高压氧气疗法作为晚期胃肝腺癌的免疫敏感化策略:一个病例报告
Wenke Li1, Jing Wei1, Pengfei Zhang1
1Gastric Cancer Center/Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Frontiers in immunology
|July 14, 2025
概括
胃肝腺癌 (HAS) 是具有侵略性的,通常对免疫疗法有抗性. 将高压氧气疗法 (HBOT) 添加到标准治疗中,导致HAS晚期患者的完整反应,这表明HBOT可以克服治疗耐药性.
科学领域:
- 在瘤学瘤学.
- 免疫治疗是一种免疫疗法.
- 高压医学的高压医学.
背景情况:
- 胃肝腺癌 (HAS) 是一种罕见的,侵袭性胃癌亚型,预后不佳.
- 免疫检查点抑制剂 (ICI) 和化疗的标准一线治疗在HAS中显示出有限的疗效.
- 瘤缺氧是限制ICI在胃癌中的有效性的关键因素.
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