微生物生物炼油厂:工程微生物用于生产多功能短链有机酸
Anuradha Singh1, Javeria1, Kavya Singh1
1Department of Chemistry, SS Khanna Girls Degree College, (A Constituent College of University of Allahabad), Prayagraj, 211 002 India.
Indian journal of microbiology
|July 14, 2025
概括
微生物生物炼油厂使用工程微生物从可再生资源生产有机酸,为石化工艺提供可持续的替代方案. 代谢工程的进步提高了绿色化工生产的效率.
科学领域:
- 生物技术是生物技术.
- 代谢工程是代谢工程.
- 可持续化学 可持续化学
背景情况:
- 有机酸生产的传统石化方法是不可持续的.
- 微生物生物炼油厂提供了一个有前途的可持续替代品.
- 利用微生物的代谢能力是生物制造的关键.
研究的目的:
- 审查微生物有机酸生产代谢工程的最新进展.
- 突出提高微生物生物炼油厂效率和生产率的战略.
- 强调生物炼油厂在可持续制造和循环经济中的作用.
主要方法:
- 对代谢工程技术的审查.
- 对路径工程策略的分析.
- 讨论应变和过程优化.
主要成果:
- 代谢工程显著提高了微生物有机酸生产效率.
- 关键策略包括途径和菌株优化.
- 过程优化进一步提高了生物炼油厂的性能.
结论:
- 微生物生物炼油厂对于可持续的生物制造至关重要.
- 这些系统减少了对化石燃料的依赖.
- 进步支持经济上可行的有机酸生产.
相关概念视频
Microbial Fermentation
406
Fermentation is a crucial anaerobic metabolic process that enables microbes to derive energy from sugar without relying on oxygen or an electron transport chain. This process is fundamental to various biological and industrial applications and is classified based on the metabolic products generated.Role of Pyruvate in FermentationPyruvate and its derivatives serve as key electron acceptors in fermentative pathways. The oxidation of NADH to regenerate NAD+ is essential for the continuation of...
406
Environmental Applications of Microorganisms
268
Microorganisms play a pivotal role in maintaining ecosystem balance by recycling essential elements such as carbon, nitrogen, and phosphorus, as well as supporting processes like bioremediation, wastewater treatment, and biofuel production.Microbes in Elemental CyclesIn the carbon cycle, microorganisms decompose organic matter, releasing carbon dioxide via aerobic respiration. This carbon dioxide is subsequently used by photosynthetic organisms to synthesize organic compounds, closing the...
268
Microbial Nutrition
315
Organisms exhibit remarkable metabolic diversity, categorized based on how they acquire energy and carbon. These strategies enable survival in various ecological niches and are essential for maintaining energy flow and nutrient cycling within ecosystems.Energy and Carbon SourcesOrganisms are classified as phototrophs or chemotrophs based on energy acquisition. Phototrophs use light as their energy source, while chemotrophs rely on oxidizing chemical compounds. Further differentiation arises...
315
Lipid Catabolism
170
Triglycerides serve as crucial long-term energy storage molecules in microorganisms, providing a dense source of metabolic energy. Their breakdown is mediated by lipases, which hydrolyze triglycerides into glycerol and free fatty acids. Each of these components follows distinct metabolic pathways, ultimately contributing to ATP synthesis and cellular energy homeostasis.Glycerol MetabolismGlycerol, released from triglyceride hydrolysis, is phosphorylated by glycerol kinase to form...
170
Microorganisms in Agriculture and Food industry
401
Microorganisms play a crucial role in agriculture and the food industry, contributing to soil fertility, crop protection, and food production. Their functions range from nitrogen fixation and biopesticide production to fermentation and food preservation, making them indispensable to sustainable farming and food safety.Role in AgricultureNitrogen-fixing bacteria, such as Rhizobium (symbiotic) and Azotobacter (free-living), convert atmospheric nitrogen into ammonia through biological nitrogen...
401
Amino Acid Catabolism
205
Microorganisms rely on proteins as an essential carbon and energy source, particularly in environments with limited polysaccharides or lipids. However, proteins are too large to cross the plasma membrane unaided, necessitating enzymatic degradation. Microbes secrete extracellular proteases and peptidases that hydrolyze proteins into peptides, which can then be transported across the membrane. Once inside the cell, intracellular proteases degrade these peptides into free amino acids, which...
205


