新型自消毒牙膏基材的抗菌效果
Shubham Bhuktar1, Sunil Kar2, Divya Batra3
1Department of Prosthodontics and Crown and Bridge, Dr. RRK Dental College Akola, Akola, Maharashtra, India.
Journal of pharmacy & bioallied sciences
|July 14, 2025
概括
与传统的聚甲基甲酸盐 (PMMA) 和银纳米颗粒相比,具有赫西丁微球的新型假牙材料对常见的口腔病原体具有优越的抗菌活性.
科学领域:
- 生物材料科学 生物材料科学
- 传染性疾病 传染性疾病
- 牙科材料 牙科材料
背景情况:
- 与假牙相关的感染是一个越来越令人担忧的问题.
- 需要具有内在抗微生物特性的创新材料.
- 自消毒假牙基提供了一个有前途的解决方案.
研究的目的:
- 评估新型假牙基材的抗菌疗效.
- 为了比较聚甲基甲酸 (PMMA) 与注入银纳米颗粒和赫西丁微球的PMMA.
主要方法:
- 测试了三组假牙基材:传统的PMMA,带有银纳米颗粒的PMMA和带有素微球的PMMA.
- 针对*Candida albicans*和*Streptococcus mutans*的抗菌疗效使用磁盘扩散和生物膜抑制试验进行了评估.
- 测量了抑制区 (ZOI) 和殖民地形成单位 (CFU) 数量.
主要成果:
- 传统的PMMA没有显示抗菌活性.
- 输入银纳米颗粒的PMMA表现出中度的疗效.
- 赫西丁微球注入的PMMA显示出最高的抗菌活性和生物膜抑制.
结论:
- 新型自消毒假牙基材,尤其是含有素微球的材料,优于传统的PMMA.
- 这些材料显示出减少假牙相关感染的巨大潜力.
相关概念视频
Antimicrobial Effectiveness
167
The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...
167
Hand hygiene
4.2K
Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
Hand washing...
Hand washing...
4.2K
Chemical Agents for Microbial Control
206
Chemicals play important roles in controlling microbial growth by targeting microbial structures and functions as sanitizers, antiseptics, disinfectants, and sterilants.Alcohols are commonly used sanitizers, effectively disrupting lipid membranes, which compromises cell integrity. They are also used as antiseptics and disinfectants due to their rapid action and versatility.Phenols and their derivatives phenolics , known for denaturing proteins and disrupting cell membranes, are particularly...
206


