相关实验视频

Updated: Sep 15, 2025

Evaluation of Antimicrobial Activities of Nanoparticles and Nanostructured Surfaces In Vitro

Evaluation of Antimicrobial Activities of Nanoparticles and Nanostructured Surfaces In Vitro

Published on: April 21, 2023

纳米-氧亚帕涂层植入物的抗菌效果对抗围植炎相关的细菌

Neeraj Sharma¹, Jyotsna Shukla¹, Shuchi Jain¹

¹Department of Prosthodontics Crown and Bridge and Implantology, Modern Dental College and Research Centre, Indore, Madhya Pradesh, India.

Journal of pharmacy & bioallied sciences

|July 14, 2025

概括

牙植入物上的纳米酸 (nHA) 涂层显著降低了细菌生长和生物膜的形成,提供了一种有前途的策略来对抗周植入炎并提高植入物存活率. 这些发现表明,nHA涂层可以提高植入物寿命.

科学领域:

生物材料科学生物材料科学
牙科植入物学牙科植入物学
微生物学微生物学

背景情况:

牙周植入物炎是导致牙植入物失败的主要原因,源自细菌生物膜.
纳米酸 (nHA) 涂层正在研究其改善植入物抗菌性质和骨质整合的潜力.

研究的目的:

评估nHA涂层牙植入物的有效性,以抑制与围植入炎相关的细菌生长.
评估nHA涂层对生物膜形成和细菌粘附的影响.

主要方法:

植入物被涂上nHA使用sol-gel技术.
对常见的围植性炎病原体 (P. gingivalis,F. nucleatum,A. actinomycetemcomitans) 进行了抗菌疗效测试,使用生物膜试验,活力试验和SEM.
使用的统计分析是ANOVA.

主要成果:

与未涂层植入物相比,nHA涂层植入物显著减少了细菌粘附和生物膜形成 (P < 0.01).
对P. gingivalis,F. nucleatum和A. actinomycetemcomitans的具体减少率分别为78%,65%和72%.
SEM证实了nHA涂层表面的生物膜积累减少,表明抗菌活性增强而不会影响生物相容性.

结论:

nHA涂层有效地抑制了植入物表面上的细菌殖民和生物膜形成.
涂有nHA的植入物显示出缓解植入周炎和改善长期植入物存活的潜力.
建议进行进一步的体内临床试验以验证这些发现.

关键词:

抗微生物涂料的使用方法细菌粘附是一种细菌粘附.生物膜是一种生物膜.牙植入物是一种牙植入物.纳米-氧亚帕提特是一种纳米-氧亚帕提特.周植入体炎 (Peri-implantitis) 是一种疾病,

更多相关视频

Effects of Mechanical Methods Used in Peri-implantitis Treatment on Implant Surface Decontamination and Roughness

Effects of Mechanical Methods Used in Peri-implantitis Treatment on Implant Surface Decontamination and Roughness

Published on: March 14, 2025

Oral Biofilm Formation on Different Materials for Dental Implants

Oral Biofilm Formation on Different Materials for Dental Implants

Published on: June 24, 2018

相关概念视频

Antimicrobial Effectiveness

Antimicrobial Effectiveness

The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...

Antimicrobial Proteins

Antimicrobial Proteins

Antimicrobial proteins are important components of the immune system. They aid the body in combating pathogens by either killing them directly or hindering their replication processes. Four main types of antimicrobial substances are interferons, the complement system, iron-binding proteins, and antimicrobial proteins.
Interferons
Interferons (IFNs) are proteins produced by lymphocytes, macrophages, and fibroblasts infected with viruses. While IFNs cannot prevent viruses from entering and...