在治疗前和治疗后对内分期病变的微生物群的评估
Hiroj Bagde1, Rishiraj Singh Karki2, Sajid Husain3
1Department of Periodontology, Chhattisgarh Dental College and Research Institute, Rajnandgaon, Chhattisgarh, India.
Journal of pharmacy & bioallied sciences
|July 14, 2025
概括
结合的内牙治疗和牙周治疗有效地减少了内牙周病变中的有害细菌. 这种治疗方法带来了显著的临床改善,强调了微生物控制对成功患者结局的重要性.
科学领域:
- 口腔微生物学 口腔微生物学
- 牙周病学 牙周病学
- 牙周内科医院 牙周内科医院 牙周内科医院
背景情况:
- 末期病变包括来自内牙和牙周源的复杂感染.
- 不同的致病细菌有助于这些具有挑战性的病变的进展.
- 在治疗前和治疗后评估微生物菌群的变化对于评估治疗疗效至关重要.
研究的目的:
- 评估结合性内牙治疗和牙周治疗对内周病变的微生物菌群的影响.
- 评估治疗后关键病原细菌的减少.
- 为了将微生物变化与患有内分期病变的患者的临床改善相关联.
主要方法:
- 30名患有内分期病变的患者接受了根管治疗,牙周除菌和抗生素.
- 在治疗前和治疗后六周收集了微生物学样本.
- 培养方法和PCR确定了Porphyromonas gingivalis,Fusobacterium nucleatum,以及Enterococcus faecalis. 这三种细菌都被发现.
主要成果:
- 治疗前的患病率:P. 牙周 (85%),F. 牙周 (85%),F. 牙周 (85%),F. 牙周 (85%),F. 牙周 (85%), 核 (75%),E.核 (75%),E.核 (75%),E.核 (75%),E.核 (75%),E.核 (75%),E.核 (75%),E.核 (75%),E.核 (75%),E.核 (75%),E.核 (75%),E.核 (75%),E.核 (75%),E.核 (75%),E. 排泄物 (60%) 的情况.
- 治疗后的患病率显著下降:P. 牙周 (30%), 牙周 (F. 核 (25%),E.核 (25%),E.核 (25%),E.核 (25%),E.核 (25%),E.核 (25%),E.核 (25%),E.核 体 (15%) (P<0.05) 的情况.
- 减少的细菌负载与减少的口袋深度和疼痛相关.
结论:
- 结合的牙周内科和牙周治疗显著减少了内周病变中的致病细菌.
- 有效的微生物控制对于成功管理这些复杂的疾病至关重要.
- 综合性治疗策略对于最佳的临床结果至关重要.
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