功能和残疾的性别差异与心脏代谢多病症的成年人使用加拿大纵向研究老化数据:一个横截面研究
Nicole I Ketter1,2, Isabelle Rash1,2, Michelle C Yang1,2
1Graduate Program in Rehabilitation Sciences, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.
Journal of multimorbidity and comorbidity
|July 14, 2025
概括
男人患心脏代谢多病症 (CM) 的患病率更高,但CM的女性报告了更多的抑郁症状,疼痛和日常生活限制. 了解CM中的这些性别差异对于有针对性的干预至关重要.
科学领域:
- 心脏病学 心脏病学
- 内分泌学 在内分泌学.
- 老年学是指老年学的学科.
- 公共卫生 公共卫生
背景情况:
- 心脏代谢多病症 (CM),定义为包括中风,糖尿病和心脏病在内的两个或更多疾病,正在上升.
- 冠状病毒与显著增加的死亡风险有关.
- 现有的研究表明,对于个体心脏代谢疾病的残疾结果存在基于性别的差异,这表明CM.可能存在类似的差异.
研究的目的:
- 为了研究心脏代谢多病症 (CM) 患病率的性别差异.
- 在被诊断为CM的个人中,检查各种残疾指标的基于性别的差异.
- 确定CM和无CM个体中预测的残疾概率,按性别分层.
主要方法:
- 来自加拿大长度老龄化研究 (CLSA) 数据的二次分析.
- 该CLSA数据集包括一个分层的随机样本,约有51000名年龄在45-85岁之间的参与者.
- 关键的独立变量包括抑郁症状,疼痛,高血压,视力障碍,日常生活活动 (ADL) 的限制和社会参与.
主要成果:
- 这项研究分析了超过1320万个人的加权人口,其中659,621人患有CM.
- 男人占CM个体的62%,表明与女性相比,CM的流行率更高.
- 与男性相比,患有CM的女性报告抑郁症状 (29%对21%),疼痛 (49%对41%) 和ADL限制 (27%对11%) 的可能性更高. 患有CM的男性报告说,他们较少参加社交活动 (23%对18%).
结论:
- 这项研究强调了心脏代谢多病症 (CM) 患者在报告残疾变量方面存在显著的基于性别的差异.
- 这些发现强调了需要将性别视为理解和管理CM的关键因素.
- 这些见解可以指导性别特定干预措施的开发,以改善CM患者的健康结果.
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