双相情感障碍中的色彩视觉障碍:系统性审查
Jason Tran1, Arnav Gupta2,3, Nicholas Fabiano4
1Department of Psychiatry, University of Toronto, Toronto, ON, Canada.
Neuroscience applied
|July 14, 2025
概括
患有双相情感障碍 (BD) 的患者表现出色彩视力受损,特别是在躁狂发作期间减少了色彩歧视. 需要进一步的研究来证实这些发现在BD的不同情绪状态.
科学领域:
- 神经科学是一个神经科学.
- 眼科医生 眼科 眼科
- 精神病学是一个精神病学.
背景情况:
- 在被诊断患有双相情感障碍 (BD) 的个体中经常观察到视力障碍.
- 神经病理生理机制可能将BD与色彩视觉能力的改变联系起来.
研究的目的:
- 系统地审查和评估有关双相情感障碍患者的色彩视觉障碍现有数据.
- 为了评估色彩歧视和色盲在BD人口中的流行情况.
主要方法:
- 在Medline,Embase和Google Scholar进行了全面的文献搜索,遵循PRISMA 2020指南.
- 纳入标准侧重于被诊断患有双相I或II型精神障碍的患者和调查色彩视觉的研究.
- 研究质量使用NIH研究质量评估工具进行评估.
主要成果:
- 包括5项涉及338名患者的研究,其中3项评估色彩歧视,2项检查色盲.
- 有证据表明,与健康对照人群相比,患有轻度至中度躁狂的患者的染色体歧视减少.
- 有限的证据表明,BD.的潜在X相关遗传模式是有限的.
结论:
- 该审查提供了证据,表明在双相情感障碍中轻度至中度的躁狂阶段,色彩歧视减少.
- 建议使用更大的样本大小和多机构数据进行进一步的研究,以验证这些发现并探索其他情绪状态.
- 未来的研究应该考虑生物标志物和混调整,以澄清色谱歧视在BD中的作用.
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