超越成本:在新兴市场采购生物类药物的基于价值的框架 - - 泰国经验
Anunchai Assawamakin1, Nilawan Upakdee2, Khachen Kongpakwattana3
1Department of Pharmacology, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand.
Journal of pharmaceutical policy and practice
|July 14, 2025
概括
一个新的多标准决策分析 (MCDA) 框架帮助泰国选择生物类药物,平衡质量和成本,以便患者更好地获得生物疗法. 这种以价值为基础的采购方法可以指导新兴市场.
科学领域:
- 制药采购 制药采购 制药采购
- 卫生经济学 卫生经济学
- 生物技术是生物技术.
背景情况:
- 生物类似药可以改善泰国等新兴市场的生物疗法.
- 生物类似药的采购决策需要评估不仅仅是成本之外的因素.
- 本研究探讨了在泰国为生物类似药物采购提供专门框架的需要.
研究的目的:
- 开发和测试泰国生物仿制药的特定环境,基于价值的采购框架.
- 利用多标准决策分析 (MCDA) 来优化生物类似物选择.
- 通过知情采购,提高获得关键生物疗法的机会.
主要方法:
- 一种混合方法的方法,结合文献审查和专家共识研讨会.
- 将现有的生物类药物选择标准映射到基于价值的采购 (VBP) 框架中.
- 通过专家投入和医院的可行性研究,开发和完善泰国特定的MCDA工具.
主要成果:
- 开发了一个定制的MCDA工具,包含七个关键标准:质量评估,稳定性评估,可比性练习,指示和推断,药物监测和风险管理,现实世界证据和切换研究以及其他考虑因素.
- 标准根据其在泰国背景中的重要性进行加权.
- 可行性研究导致了标准权重的调整和医院特定优先事项的纳入.
结论:
- 已经建立了一个全面的,特定于背景的MCDA工具,用于泰国生物类药物采购.
- 该框架平衡了科学严谨性和实际考虑,以优化生物类似物选择.
- 这种方法为其他新兴市场提供了一个模型,以改善其生物类似物采购策略,提高质量和成本效益.
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