在患有高近视症的患者中,眼内压和胸腔微循环之间的相关性
Dongjie Song1,2, Yutong Han3, Zongchan Zhang2
1Department of Ophthalmology, the Fourth Affiliated Hospital of School of Medicine, and International School of Medicine, International Institutes of Medicine, Zhejiang University, Yiwu, China, 322000.
International journal of medical sciences
|July 14, 2025
概括
高近视与更高的眼内压力 (IOP) 和降低胆道血管性有关. 这项研究表明,升高的内脉压可能会影响胆道微循环,可能会影响高近视的进展.
科学领域:
- 眼科医生 眼科 眼科
- 医疗成像医学成像
- 视网膜研究 视网膜研究
背景情况:
- 高近视 (HM) 是全球视力障碍的重要原因之一.
- 胸膜在HM进展中至关重要,眼内压力 (IOP) 也可能发挥作用.
- 在HM患者中,IOP和胆道微循环之间的关系尚不清楚.
研究的目的:
- 为了研究高近视的个体中内压力和胆道微循环之间的相关性.
- 使用扫描源光学连贯断层扫描血管学 (SS-OCTA) 进行详细的微循环分析.
主要方法:
- 118名参与者的横截面观察研究 (64名HM,54名轻度至中度近视).
- 收集的数据包括轴长 (AL),球形相当 (SE) 和中角膜厚度 (CCT).
- 使用非接触性度计测量了IOP,并对CCT进行了校正. 通过SS-OCTA分析胸膜厚度和血管参数.
主要成果:
- 与轻度至中度近视眼相比,高近视眼的眼睛显示更高的校正IOP和降低的胸膜厚度,血管体积和筋膜体积.
- 在HM眼中,观察到冠状管层密度增加和冠状管血管指数下降.
- 在HM患者中,校正的IOP与SE相关,胸腔厚度,胸腔血管指数和胸腔层密度相关,但与AL无关.
结论:
- 高近视眼睛表现出更高的IOP水平,与SE负相关,但不是AL.
- 升高的内膜压力与特定斑点区域的胆道厚度和血管性降低有关.
- IOP和胆道微循环之间的潜在联系可能会导致高近视的进展.
更多相关视频
08:55Translaminar Autonomous System Model for the Modulation of Intraocular and Intracranial Pressure in Human Donor Posterior Segments
Published on: April 24, 2020
3.2K
07:18Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography
Published on: February 18, 2022
1.9K
相关概念视频
Glaucoma: Overview
775
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
775
Open Angle Glaucoma: Treatment
579
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
579
Angle Closure Glaucoma: Treatment
697
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
697
