胃衰和全身性红斑狼:美国国家数据库分析的倾向性得分匹配研究
Noppachai Siranart1, Pannathorn Nakaphan2, Thanathip Suenghataiphorn3
1Division of Gastroenterology Hepatology and Endoscopy, Brigham and Women's Hospital Boston Massachusetts USA.
概括
系统性红斑狼 (SLE) 与胃衰竭有关,导致更长的住院时间,成本增加和更多的干预. 在SLE患者中早期评估胃衰竭对于更好的管理和更少的并发症至关重要.
科学领域:
- 胃肠病学 胃肠病学
- 类风湿病学 类风湿病学
- 医疗保健服务研究 医疗服务研究
背景情况:
- 胃肠道问题在全身性红斑狼 (SLE) 中很常见.
- 胃衰竭和SLE之间的特定关系还没有得到很好的定义.
- 了解这种关联对于患者护理至关重要.
研究的目的:
- 调查胃衰竭和SLE之间的关联.
- 为了比较临床特征,并发病症和SLE患者和没有SLE患者之间的住院结果,这些患者患有胃.
- 评估胃衰竭对SLE患者的影响.
主要方法:
- 从国家住院样本 (NIS) 数据库 (2016-2021) 的数据分析.
- 在SLE和非SLE群体中对胃衰竭患者进行分类.
- 使用统计分析对临床数据,并发症,住院细节和结果进行比较,包括倾向性-得分匹配.
主要成果:
- 系统性红斑狼 (SLE) 在胃衰竭患者中明显更为普遍 (1.6%与0.7%相比).
- 患有SLE和胃衰竭的患者经历了更长的住院时间 (β=0.31),更低的住院费用 (平均差别为4761美元),以及更高的干预需求 (OR 1.31).
- 与倾向性得分相匹配的65岁以上的SLE患者与非SLE患者相比,住院费用更高 (平均差异为7287美元).
结论:
- 胃衰竭与系统性红斑狼 (SLE) 有着显著的关联.
- 在SLE患者的胃衰竭与延长住院时间,增加成本和对干预措施的需求增加有关.
- 建议立即评估SLE患者的胃衰竭,以便及时管理和减少并发症.
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