在瑞士增加HPV疫苗接种范围:投资回报分析
Nikolaos Kotsopoulos1,2, Mark P Connolly1,3, Selim Nur4
1Global Market Access Solutions Sàrl, Health Economics, Chardonne, Switzerland.
Journal of medical economics
|July 14, 2025
概括
到2030年在瑞士实现90%的人类乳头瘤病毒 (HPV) 疫苗接种覆盖率,将带来显著的经济效益. 这项研究预计将带来巨大的社会和财政收益,并为公共卫生倡议带来有利的投资回报.
科学领域:
- 公共卫生 公共卫生
- 卫生经济学 卫生经济学
- 流行病学 流行病学
背景情况:
- 人类乳头瘤病毒 (HPV) 感染造成了重大的公共卫生负担,包括癌症,大量的医疗费用和生产力损失.
- 瑞士目前的HPV疫苗接种覆盖率低于最佳水平,需要采取战略来改善接种率.
研究的目的:
- 评估到2030年将HPV疫苗覆盖率提高到90%的社会和财政收益,对瑞士所有符合条件的性别和年龄组.
- 为了比较一个更高的VCR场景与当前覆盖率的经济影响.
主要方法:
- 采用动态传播模型来预测非价值HPV疫苗增加的VCR的影响.
- 经济效益,包括避免死亡率,发病率,医疗保健成本和生产力损失,被量化并与疫苗接种成本进行比较.
- 对社会和财政回报的收益成本比率 (BCRs) 用3%的折扣率计算在100年时间范围内.
主要成果:
- 预计较高的VCR场景将节省医疗保健费用8.34亿瑞士法郎.
- 避免死亡和预防发病的社会收益估计分别为2.18亿瑞士法郎和1.81亿瑞士法郎.
- 财政收益包括1亿瑞士法郎的税收收入和8500万瑞士法郎的避免残疾成本,社会和财政BCR为1.5和1.2.
结论:
- 预计到2030年实现90%的HPVVCR将为瑞士政府带来有利的经济回报.
- 据估计,在更高的视频录像机上投资的每1瑞士法郎,在接种疫苗的队伍的一生中,会产生1.5瑞士法郎的社会回报和1.2瑞士法郎的财政回报.
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