通过机器学习,根据常见的动脉来预测内动脉系统风险
Yuhao Tong1, Qingyi Zhang2, Feng Zhang3
1College of Medical Information and Artificial Intelligence, Shandong First Medical University, Qingdao road, Jinan, 250117, Shandong, China.
Medical & biological engineering & computing
|July 14, 2025
概括
使用常见动脉 (CCA) 特征的机器学习模型可以预测内动脉 (ICA) 疾病风险. 这提供了一个具有成本效益的查工具,用于早期预防中风.
科学领域:
- 血管医学 血管医学
- 医疗成像医学成像
- 机器学习 机器学习
背景情况:
- 早期识别内动脉 (ICA) 疾病对于预防中风至关重要.
- 目前的诊断方法往往是昂贵的,需要专门的专业知识,限制了可访问性.
- 开发高效的查工具对于及时干预至关重要.
研究的目的:
- 开发一个可解释的机器学习 (ML) 模型来预测ICA疾病风险.
- 利用常见的动脉 (CCA) 功能来进行可访问和高效的查.
- 从CCA数据中识别ICA疾病的关键预测因素.
主要方法:
- 分析了来自1612名患者的临床数据 (806名高风险,806名低风险ICA疾病).
- 使用CCA特征训练五个ML模型:血液流动,亲密介质厚度,内部直径,年龄和性别.
- 使用准确度,灵敏度,特异性,AUC-ROC和F1得分来评估模型性能;用于预测因子识别的SHAP分析.
主要成果:
- 支持矢量机 (SVM) 模型实现了最高的性能 (精度84.9%,AUC92.6%).
- SVM的性能优于神经网络 (准确率为81.4%,AUC为89.8%).
- SHAP分析确定了CCA血流 (负相关性) 和亲密介质厚度 (正相关性) 作为主要预测因素.
结论:
- 使用可解释的ML分析CCA的血液动力学和结构特征,可以有效预测ICA疾病风险.
- 基于SVM的框架提供了一个具有成本效益的早期干预查工具,特别是在资源有限的环境中.
- 建议在多中心队列中进一步验证.
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