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Updated: Sep 15, 2025

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[动物模型中的肝脏瘤病理]

Thomas Metzler1,2, Margaret Tulessin1,2, Tanja Groll1,2

  • 1Vergleichende experimentelle Pathologie (CEP), School of Medicine and Health, Technische Universität München, München, Deutschland.

Pathologie (Heidelberg, Germany)
|July 14, 2025
PubMed
概括

各种动物模型有助于肝癌研究. 鼠标模型是常见的,但狗和猫的自发瘤为肝癌机制和治疗提供了独特的见解.

关键词:
比较病理学比较病理学接口 接口 接口 接口鼠标模型 鼠标模型伴侣动物的自发性肝脏瘤兽医病理学 兽医病理学

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Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
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