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Updated: Sep 15, 2025

An Inexpensive Adaptation of a Commercial Microwave Reactor for Solid Phase Peptide Synthesis
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An Inexpensive Adaptation of a Commercial Microwave Reactor for Solid Phase Peptide Synthesis

Published on: November 22, 2024

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合成的小分子催化剂

Nihar R Panigrahi1, Shahrukh M Khan1, Handoko1

  • 1Department of Chemistry, New York University, 100 Washington Square East, New York, New York 10003, United States.

Journal of the American Chemical Society
|July 14, 2025
PubMed
概括

一种新的小分子催化剂能够使用更绿色的溶剂和更少的试剂进行有效的合成. 这一突破简化了的生产,减少了治疗开发中的浪费和环境影响.

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Peptide Bonds02:43

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A peptide bond covalently attaches amino acids through a dehydration reaction. One amino acid's carboxyl group and another amino acid's amino group combine, releasing a water molecule. The resulting bond is the peptide bond. The products that such linkages form are peptides. As more amino acids join this growing chain, the resulting chain is a polypeptide. Each polypeptide has a free amino group at one end. This end has the N-terminal, or the amino-terminal, and the other end has a free...
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