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用于生物医学应用的部分可降解Ti-Mg复合材料:最近的进展和未来的前景

Zhongjie Li¹, Hao Xu², Xuecheng Cai³

¹Laboratory for Liquid-Solid Structural Evolution & Processing of Materials (Ministry of Education), School of Materials Science & Engineering, Shandong University, Jinan, 250061, PR China; Shanghai Key Lab of Advanced High-temperature Materials and Precision Forming, School of Materials Science and Engineering, Shanghai Jiao Tong University, Shanghai, 200240, PR China.

Acta biomaterialia

|July 14, 2025

概括

- (Ti-Mg) 复合材料由于其可调节的降解和骨整合特性,为生物活性金属植入物提供了有希望的替代品. 先进的制造技术使得量身定制的微观结构能够提高骨透和机械支.

科学领域:

生物材料科学生物材料科学
材料工程材料工程材料工程
整形外科植入物整形外科植入物

背景情况:

传统的多孔 (Ti) 合金在骨整合和机械支方面存在局限性.
(Mg) 合金具有生物降解性和生物活性,但缺乏足够的机械稳定性.
Ti-Mg复合材料结合了Ti和Mg的优点,用于先进的骨科应用.

研究的目的:

为生物活性金属植入物提供Ti-Mg复合材料近期进展的全面审查.
分析制造技术,微结构设计和Ti-Mg复合材料的性能优化.
讨论Ti-Mg复合材料在增强骨整合和骨透中的潜力.

主要方法:

高级制造技术的分类和分析:粉末金 (PM),融透和液体金属处理 (LMD).
审查宏观结构设计原则和微观结构特征.
系统地讨论机械性能,降解行为,以及体外/体内生物评估.

主要成果:

Ti-Mg复合材料表现出可编程的降解介导的孔形成,促进骨质整合和骨浸透.
Ti矩阵提供了与多孔Ti合金相比较的机械支.
可调节的微结构架构和性能优化是关键优势.

结论:

Ti-Mg复合材料代表了下一代生物活性金属植入物的前沿,具有特定区域的降解概况.
先进的制造使生物模拟结构工程和微观结构优化成为可能.
进一步开发Ti-Mg复合材料具有通过材料创新的临床转化显著潜力.

关键词:

生物相容性生物相容性接口接口接口接口机械性质机械性质部分降解降解部分降解这是一种Ti-Mg复合材料.

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