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放射治疗中的性别差异:批判性审查

Emma D'Ippolito¹, Roberta Grassi¹, Cristiano Grossi²

¹Department of Precision Medicine, University of Campania "L. Vanvitelli", Naples 80138, Italy.

Critical reviews in oncology/hematology

|July 14, 2025

概括

放射治疗的有效性因人而异,有记录的放射敏感性性别差异. 当前的指导方针往往忽视了这一关键的性别/性别因素,影响了治疗结果.

科学领域:

在瘤学瘤学.
辐射瘤学辐射瘤学
医学伦理医学伦理

背景情况:

放射治疗是癌症的关键治疗方法,但个人的放射敏感性各不相同.
放射性敏感性的基于性别的差异是已知的,但在临床实践中经常被忽视.
当前的放射治疗指南和试验经常缺乏性别/性别考虑.

研究的目的:

在放射治疗中批判性地讨论有关性别角色的证据.
突出性别对治疗耐受性和疗效的影响.
倡导个性化,性别意识的癌症护理.

主要方法:

使用PubMed. 的文献评论.
手动搜索相关研究.手动搜索相关研究.
包括来自clinicaltrials.gov.gov的数据.

主要成果:

一份叙事报告和对现有证据的批判性讨论.
对性别和放射治疗结果之间的相互作用进行分析.
关于治疗耐受性和疗效差异的证据.

结论:

需要个性化治疗策略.
性别意识的临床试验对于公平的结果至关重要.
优化患者护理需要整合性别/性别因素.

关键词:

癌症癌症癌症癌症性别性别性别性别在瘤学瘤学.精准医学是一门精准的医学.放射疗法是一种放射治疗.性差异性差异性差异性差异性差异性差异性差异性

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