根据医院的一天对输血有效性的变化:一个多中心的回顾性研究
Nicholas A Bosch1,2, Anica C Law1, Nareg H Roubinian3,4
1The Pulmonary Center, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA.
Journal of hospital medicine
|July 14, 2025
概括
包装红细胞 (pRBC) 输血的时间会影响患者的治疗结果. 早期输血显示有好处,而晚期输血可能会增加死亡风险,这突显了输血时间在医院护理中的重要性.
科学领域:
- 临床医学 临床医学
- 血液学 血液学 血液学
- 医疗保健服务研究 医疗服务研究
背景情况:
- 输血的包装红细胞 (pRBCs) 是常见的血红蛋白<7.0 g/dL.
- 在住院期间输血时间对疗效的影响尚不清楚.
研究的目的:
- 为了调查pRBC输血的效果是否基于入院后的时间而异质.
- 确定pRBC输血时间和患者结果之间的关联.
主要方法:
- 多中心回顾性队列研究 (2016-2022) 使用Premier Inc.AI医疗保健数据库.
- 包括成人住院患者与衡量血红蛋白的接触 1-7天.
- 使用回归不连续性来分析pRBC输血与没有输血在指数日Hb<7.0g/dL时.
主要成果:
- 从997,277次遭遇中分析了2,293,021个索引日.
- 输血在第一天显示出好处 (RD:-2.9%).
- 输血在第6天 (RD:3.3%) 和第7天 (RD:4.1%) 与危害相关,具有显著的相互作用 (p < .0001).
结论:
- 输血时间显著改变了pRBC输血和结果之间的关联.
- 早期住院输血 (1日) 与益处有关.
- 晚些时候的住院输血 (6-7天) 与危害有关,包括死亡率或临终关怀退院.
相关概念视频
02:45Blood Transfusion and Agglutination
11.2K
Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
11.2K
01:15Blood Transfusion
818
Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
818