加拿大艾滋病毒暴露前预防药物 (PrEP) 吸收和使用的障碍和促进因素:一个范围审查协议
Amani Chabikuli1, Debapriya Chakraborty2, Carolyn Ziegler3
1University of Toronto - St George Campus, Toronto, Ontario, Canada.
BMJ open
|July 14, 2025
概括
加拿大的艾滋病毒暴露前预防药物 (PrEP) 获取障碍阻碍了其吸收和使用. 本次审查确定了改善PrEP获取和整合到艾滋病毒预防战略的因素.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 预防艾滋病毒 预防艾滋病毒
背景情况:
- 尽管取得了进展,但在加拿大,仍存在重大障碍,阻碍人们获得艾滋病毒暴露前预防药物 (PrEP).
- 结构性,社会和系统性因素影响了PrEP的吸收和使用,影响了坚持和保留.
- 了解这些障碍对于有效的艾滋病预防策略至关重要.
研究的目的:
- 对加拿大PrEP吸收和使用的障碍和促进者的现有证据进行范围审查.
- 确定影响PrEP获取和融入艾滋病毒预防工作的因素.
- 为未来的研究,政策和干预提供信息,以改善PrEP的利用.
主要方法:
- 对加拿大有资格接受或使用PrEP的艾滋病病毒阴性个体的研究进行范围审查.
- 在关键数据库 (MEDLINE,Embase,PsycINFO等) 进行了搜索. 从2016年起,没有语言限制.
- 两个独立的审稿人选了标题,摘要和全文;数据被叙事分析.
主要成果:
- 该审查综合了加拿大的PrEP障碍和促进者的主题,趋势和证据缺口.
- 小组分析侧重于关键人群,以了解差异性影响.
- 调查结果将提供当前证据格局的全面概述.
结论:
- 识别障碍和促进因素对于优化加拿大PrEP实施至关重要.
- 这些发现将指导制定有针对性的干预和政策.
- 改善PrEP的获取和使用可以在全国范围内对艾滋病毒预防工作做出重大贡献.
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