通过基于社区的有氧运动训练来增强乳腺癌幸存者的认知功能:混合I型有效性实施研究的协议,采用随机对照设计
Diane K Ehlers1, Jessica D Austin2, Brenda Ernst3
1Department of Quantitative Health Sciences, Mayo Clinic, Phoenix, Arizona, USA ehlers.diane@mayo.edu.
BMJ open
|July 14, 2025
概括
这项研究调查了基于社区的有氧运动是否可以改善乳腺癌幸存者的认知功能. 乳腺癌推理和活动干预 (BRAIN) 试验评估了炼的有效性和实施的成功.
科学领域:
- 在瘤学瘤学.
- 神经科学是一个神经科学.
- 运动科学 运动科学
背景情况:
- 癌症相关认知衰退 (CACD) 显著影响患有乳腺癌的女性.
- 缓解CACD的干预措施有限,对炼有效性的高质量研究很少.
- 将练习干预转化为社区设置提出了实施挑战.
研究的目的:
- 研究以社区为基础的有氧运动计划的有效性,以改善乳腺癌妇女的认知功能.
- 使用RE-AIM框架收集有关有氧运动干预措施实施成功情况的数据.
- 为了解决乳腺癌幸存者中CACD研究不足的结果.
主要方法:
- 一个混合型I有效性实施研究,对160名被诊断为I-IIIa阶段乳腺癌的女性进行了研究.
- 1:1随机对照试验,比较6个月的有氧运动计划与6个月的虚拟健康教育对照.
- 评估认知表现,患者报告的结果,身体活动,心肺健康和脑部MRI. 实施结果 (RE-AIM) 也被衡量.
主要成果:
- 这个部分不在所提供的摘要中.
结论:
- 这个部分不在所提供的摘要中.
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