长期神经认知和行为结果在患有非综合征性关突症的患者
Jacqueline Ihnat1, Kevin Gao Hu1, Jeremy Goss1
1Division of Plastic Surgery, Department of Surgery, Yale School of Medicine, 330 Cedar Street, Boardman Building, New Haven, CT, 06510, USA.
概括
长期的认知功能在关突症患者是与一般人群相比较的,但视觉运动整合缺陷被注意到. 注意力缺陷/多动症障碍 (ADHD) 和自闭症行为更为普遍.
科学领域:
- 神经科学是一个神经科学.
- 整形外科 整形外科 整形外科
- 发展心理学 发展心理学
背景情况:
- 头骨突症是一种先天性缺陷,涉及到头骨部的过早融合.
- 早期的手术纠正是非综合征性关节缩症的标准.
- 关于神经认知和行为的长期结果需要进一步调查.
研究的目的:
- 为了评估那些在婴儿期接受了骨修复手术的个体的长期认知能力和行为.
- 为了确定在青春晚期和成年早期潜在的神经发育挑战.
主要方法:
- 追溯鉴定16岁以上为非综合征性关突症进行婴儿手术的患者.
- 进行了标准化神经认知测试 (BEERY,WASI) 和行为评估 (CAARS-2,ASR,SRS-2,BRIEF).
- 分析了数据,以比较患者得分与一般人口规范.
主要成果:
- 神经认知得分 (WASI FSIQ-4,PRI,VCI) 与一般人群的得分相当.
- 在视觉运动整合 (BEERY VMI,VP,MC) 中观察到显著的缺陷.
- 发现了较高的注意力缺陷/多动症障碍 (ADHD) 和自闭症谱系障碍 (ASD) 的特征.
结论:
- 被手术治疗关突症的个体表现出典型的一般神经认知,但可能具有特定的视觉运动整合缺陷.
- 在这个群体中,ADHD和自闭症相关行为发生率增加.
- 这些发现支持针对受影响个人及其家属的查和早期干预.
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