在40岁以上的男性中发展良性前列腺增生的全球,区域和国家终身风险:从1990年到2021年的基于人口的横截面研究
Yongming Chen1, Yuhao Li2, Lingfeng Li1
1Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100005, People's Republic of China.
Tropical medicine and health
|July 14, 2025
概括
在全球范围内,40岁前患良性前列腺增生症 (BPH) 的终身风险为27.29%,区域差异很大. 预计这种风险将保持稳定,突出显示需要有针对性的BPH管理策略.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 良性前列腺增生 (BPH) 是一种常见的疾病,影响老年男性,显著影响生活质量.
- 对终身BPH风险的全面全球估计是有限的,需要更新评估.
- 2021年全球疾病负担 (GBD) 为流行病学分析提供了强大的数据集.
研究的目的:
- 量化发展良性前列腺增生 (BPH) 的全球和区域终身风险.
- 分析不同年龄组,地区和社会人口统计指数 (SDI) 的BPH风险趋势.
- 为BPH提供有针对性的预防和管理策略.
主要方法:
- 利用"调整为多个初级 (AMP) "的方法来估计40岁以上男性的终身BPH风险.
- 分析了GBD 2021的数据,涵盖了从1990年到2021年的204个国家和地区.
- 根据年龄,地区和社会人口统计指数 (SDI) 进行分层分析,以确定风险变化.
主要成果:
- 从40岁起的全球BPH终身风险在2021年估计为27.29%,区域差异很大.
- 东欧的风险最高 (37.57%),撒哈拉以南非洲的风险最低 (13.66%).
- 终身风险因SDI而异,在高中SDI地区达到峰值 (31.51%),影响50-70岁男性最多,自1990年以来,全球逐渐增加.
结论:
- 本研究提供了对终身BPH风险的全面全球评估,揭示了区域和年龄相关的显著差异.
- 调查结果突出了针对性预防和管理策略的需要,特别是在高风险人群和地区.
- 持续监测和有针对性的干预措施对于减轻日益增长的全球BPH负担至关重要.
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