氧化平衡得分与睡眠障碍之间的相互作用及其对中风患病率的影响:跨越NHANES 2005-2018年的横截面研究
Huajian Lin1, Chunhua Liu, Zegen Ye
1Lishui Hospital of Traditional Chinese Medicine Affiliated to Zhejiang University of Chinese Medicine, Lishui City, Zhejiang Province, China.
Medicine
|July 15, 2025
概括
睡眠不足和饮食中低抗氧化剂平衡会增加中风风险,特别是当它们结合在一起时. 改善抗氧化剂摄入量可能有助于减轻睡眠障碍患者的这种风险.
科学领域:
- 心血管健康 心血管健康
- 营养科学 营养科学
- 睡眠医学 睡眠医学
背景情况:
- 不健康的生活方式是已知的中风风险因素.
- 睡眠障碍和饮食氧化平衡对中风患病率的综合影响仍未得到充分研究.
研究的目的:
- 为了检查睡眠障碍与氧化平衡得分 (OBS) 之间关于中风患病率的相互作用.
- 分析来自大量多样化的成年人群的数据,以了解这些关系.
主要方法:
- 利用了来自国家健康和营养检查调查 (2005-2018) 的28253名成年人的数据.
- 采用多变量逻辑回归,相互作用测试和受限立方线分析.
- 评估氧化平衡得分 (OBS) 连续和四分位数,分析赔率比率 (OR) 和95%置信区间 (CI).
主要成果:
- 较低的OBS与中风患病率的降低有关 (OR 0.98).
- 睡眠障碍独立增加了中风风险 (OR 1.52).
- 睡眠障碍与最低OBS四分位数之间的显著相互作用增加了中风患病率 (OR 1.02),特别是在老年人,男性和非西班牙裔黑人中.
结论:
- 睡眠障碍和氧化平衡不佳与更高的中风患病率有关.
- 这种相互作用在氧化平衡最低水平时最为明显.
- 提高抗氧化剂摄入量的策略可能有助于降低睡眠障碍患者中风风险.
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