相关实验视频

Updated: Sep 15, 2025

Author Spotlight: Overcoming Anti-VEGF Resistance Through Advanced Vascular Morphology Assessment in Choroidal Neovascularization

Author Spotlight: Overcoming Anti-VEGF Resistance Through Advanced Vascular Morphology Assessment in Choroidal Neovascularization

Published on: August 11, 2023

近视性黄斑新血管化的发生率和临床实践:全国人口基的队列研究

Masahiro Akada¹, Masahiro Miyake¹, Masayuki Hata¹

¹Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.

Ophthalmology science

|July 15, 2025

概括

这项研究表明,近视性黄斑新血管化 (mMNV) 影响女性比男性更多,超过一半的患者接受抗VEGF治疗. 发病率和治疗模式为mMNV管理提供了洞察力.

科学领域:

眼科医生眼科眼科
流行病学流行病学
医疗保健服务研究医疗服务研究

背景情况:

近视性黄斑新血管化 (mMNV) 是高度近视的个体视力丧失的重要原因.
了解mMNV的流行病学和治疗模式对于有效的公共卫生战略至关重要.

研究的目的:

确定近视性黄斑新血管化 (mMNV) 在日本的发病率和治疗模式.
分析特定于年龄和性别的发病率以及针对mMNV的抗VEGF治疗使用情况.

主要方法:

一项基于人口的队列研究,利用日本国家健康保险索赔数据库从2016年到2022年.
识别新发 mMNV 病例并计算发病率.
评估初始治疗模式,包括选择抗VEGF剂和注射频率.

主要成果:

确定了超过45,000个mMNV病例,其粗发病率为每10万人年5.17,女性 (7.12) 比男性 (3.12) 高.
发病的平均年龄为男性59.3岁,女性63.5岁.
52.6%的患者接受了抗VEGF治疗,阿弗利伯塞普 (56.5%) 比拉尼比祖马布 (43.5%) 更常见.

结论:

这项研究提供了日本mMNV流行病学和抗VEGF治疗模式的最广泛的基于人口的数据.
这些发现突显了mMNV发病率的性别差异,并为使用抗VEGF疗法提供了信息.
结果提供了宝贵的见解,对mMNV的医疗和社会影响在广泛的反-VEGF实施后.

关键词:

一个自由的概念.抗-VEGFF的方法是什么近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近视近近视性黄斑新血管化拉尼比祖马姆是什么意思

更多相关视频

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

In Vivo Multimodal Imaging and Analysis of Mouse Laser-Induced Choroidal Neovascularization Model

In Vivo Multimodal Imaging and Analysis of Mouse Laser-Induced Choroidal Neovascularization Model

Published on: January 21, 2018

相关概念视频

Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

Open Angle Glaucoma: Treatment

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

Angle Closure Glaucoma: Treatment

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...