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Updated: Sep 15, 2025

Fluorescence Assays for the Study of Mycobacterium tuberculosis Interaction with the Immune Receptor SLAMF1
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结核菌的效应蛋白PE5劫持了宿主CRL2泛素结合酶复合体

Bala T S A Madduri1, Omair Vehra1, Ahri Han1

  • 1New Jersey Medical School, Rutgers Health, Newark, NJ.

bioRxiv : the preprint server for biology
|July 15, 2025
PubMed
概括

结核菌PE5蛋白与宿主CRL2-KLHDC2泛素酶发生相互作用. 这种相互作用导致PE5降解和KLHDC2自化增加,为Mtb毒性提供了新的见解.

关键词:
在C端的降解.细菌病原体的产生.主体-病原体相互作用蛋白质的稳定性 蛋白质的稳定性无处不在的化

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