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Updated: Sep 15, 2025

Assessment of Resistance to Tyrosine Kinase Inhibitors by an Interrogation of Signal Transduction Pathways by Antibody Arrays
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在氨酸激酶中识别氨酸的主要分子决定因素的结构识别揭示了促进瘤和抑制功能

Nuo Cheng1, Luis R Millán-Barea2, Marc Creixell2

  • 1Cancer Research UK Cambridge Institute, University of Cambridge, UK.

bioRxiv : the preprint server for biology
|July 15, 2025
PubMed
概括

蛋白质激酶使用光化来创建双胞胎光氨酸 (pTyr) 位点,这对于细胞循环控制至关重要. 这种机制涉及特定的识别部位,影响癌症的进展和白血病的发展.

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