相关实验视频

Updated: Sep 15, 2025

Using Microtiter Dish Radiolabeling for Multiple In Vivo Measurements Of Escherichia coli pppGpp Followed by Thin Layer Chromatography
06:30

Using Microtiter Dish Radiolabeling for Multiple In Vivo Measurements Of Escherichia coli pppGpp Followed by Thin Layer Chromatography

Published on: June 4, 2019

6.1K

PBP1B的酶活性补偿了细胞过度生产ppGpppp中的β-乳糖介导的PBP2抑制

Sarah E Anderson, Isabella E Mack, Petra Anne Levin

    bioRxiv : the preprint server for biology
    |July 15, 2025
    PubMed
    概括

    升高的警报激素 (p) pGpp水平,通过通过PBP1B增强细胞壁合成,使大肠杆菌对特定β-乳糖抗生素产生耐药性. 这一发现将营养状况与抗生素疗效联系起来.

    更多相关视频

    Using the Overlay Assay to Qualitatively Measure Bacterial Production of and Sensitivity to Pneumococcal Bacteriocins06:05

    Using the Overlay Assay to Qualitatively Measure Bacterial Production of and Sensitivity to Pneumococcal Bacteriocins

    Published on: September 30, 2014

    13.7K
    Identifying the Binding Proteins of Small Ligands with the Differential Radial Capillary Action of Ligand Assay DRaCALA09:26

    Identifying the Binding Proteins of Small Ligands with the Differential Radial Capillary Action of Ligand Assay DRaCALA

    Published on: March 19, 2021

    3.6K

    相关概念视频

    Stringent Response in E. coli01:23

    Stringent Response in E. coli

    Bacterial growth is closely tied to nutrient availability, with cells proliferating exponentially under favorable conditions and entering a stationary phase when resources become scarce. This transition is mediated by a regulatory mechanism known as the stringent response, which allows bacteria to adapt to nutrient deprivation by modulating gene expression and metabolic activity.During nutrient scarcity, intracellular amino acid levels decline. It results in the accumulation of uncharged tRNAs...
    56
    Coordination of Gene Expression Processes in Bacteria01:29

    Coordination of Gene Expression Processes in Bacteria

    The DNA replication, transcription, and translation processes are intricately coupled in bacteria, allowing efficient gene expression and rapid protein synthesis. While this physical and functional coordination is advantageous, it introduces challenges that bacteria overcome through specific regulatory mechanisms.Coupling of Replication, Transcription, and TranslationThe coupling of replication, transcription, and translation is a hallmark of bacterial gene expression. As the replisome unwinds...
    156
    Other Glycolytic Pathways01:24

    Other Glycolytic Pathways

    The pentose phosphate pathway (PPP) operates in parallel with glycolysis, facilitating the metabolism of both pentoses and glucose. This pathway consists of two distinct phases: the oxidative and non-oxidative phases. While it does not directly generate ATP, the intermediates formed during the process can integrate into glycolysis, contributing to cellular energy metabolism when required.Oxidative Phase: NADPH ProductionThe oxidative phase of the pentose phosphate pathway is primarily...
    223