发生率,相关异常和右心结局:沙特阿拉伯的基于登记册的研究
Naif S ALGhasab1, Bandar Alshehri2, Sulaman ALMesned3
1Department of Internal Medicine, Medical Collage, University of Ha'il', Ha'il, Saudi Arabia.
Journal of the Saudi Heart Association
|July 15, 2025
概括
德克斯托卡迪,心脏右侧位置,发生在约1在28,571怀孕. 存活率因网站类型而异,异构体患者面临更高的死亡率.
科学领域:
- 心脏病学 心脏病学
- 医学遗传学 医学遗传学
- 发育生物学 发展生物学
背景情况:
- 德克斯特罗卡迪亚是心脏的右侧定位,可能与其他发育不良有关.
- 关于德克斯托卡迪患者的综合结果的研究有限.
研究的目的:
- 为了确定心脏和非心脏形的发病率在dextrocardia.
- 为了分析长期随访和生存结果的患者与dextrocardia.
主要方法:
- 从1975年至2016年,对德克斯托卡迪病例的回顾性图表审查.
- 分析了259,246个跨胸腔心声图,其中包括357名德克斯托卡迪患者.
主要成果:
- 德克斯托卡迪亚的发病率大约为每1万个怀孕中0.35.
- 常见的心脏异常包括隔膜缺陷;总体生存率为83%,根据网站类型而异 (Situs inversus 96%,Situs solitus 91%,Situs模糊55%).
- 肺高血压显著降低了生存率;胃肠道和泌尿器官异常是常见的非心脏问题.
结论:
- 这项研究代表了德克斯托卡迪最大的区域队列,提供了社区特定的见解.
- 复杂的先天性心脏病在网站单体和异构组中更为普遍.
- 同位体组的死亡率明显高于网站单身和网站反向组.
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