在椎患者中胆病的高患病率和反之亦然:一个前性的多中心研究
Hakan Kulacoglu1, Alpaslan Sahin2, Celil Ugurlu3
1Department of General Surgery, Ankara Hernia Center, Ankara, TUR.
Cureus
|July 15, 2025
概括
胆病和带经常共存,共享诸如肥胖等危险因素. 超过26.5或28.8的BMI可能预测这些情况,这表明需要进一步研究的临床联系.
科学领域:
- 胃肠病学和整体外科
- 临床流行病学 临床流行病学
- 肥胖问题研究研究
背景情况:
- 胆病 (CL) 和椎 (UH) 经常共存,但它们之间的关系尚不清楚.
- 包括肥胖和女性性别在内的共同风险因素表明潜在的病理生理联系.
- 缺乏可靠的前性多中心数据阻碍了对它们的关联的准确评估.
研究的目的:
- 估计在CL患者中UH的患病率,反之亦然.
- 确定CL和UH同时发生的独立风险因素.
- 在这个协会中评估身体质量指数 (BMI) 的预测值.
主要方法:
- 对278名患有CL或UH的成年患者进行了前性,多中心的横截面研究.
- 临床和放射学评估以分类参与者.
- 多变量后勤回归和ROC曲线分析以确定风险因素和BMI值.
主要成果:
- 44%的CL患者患有UH,30%的UH患者患有CL.
- 肥胖 (BMI ≥30) 是同时发生的重要危险因素 (OR: 3.443). 女性的性别也很重要 (OR:0.221).
- 最佳的BMI截止值为26.5kg/m2用于预测HH患者的CL,为28.8kg/m2用于预测HH患者的CL.
结论:
- 临床相关性 临床相关性 临床相关性 临床相关性 临床相关性 临床相关性 临床相关性 临床相关性
- 在患有高BMI的UH患者中,超声波查胆病可能有助于手术规划.
- 对共同的病理生理机制进行进一步的研究是有必要的.
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