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在沙特阿拉伯麦加的献血者血清查:对输血传染病的7年后期研究

Amr J Halawani¹, Afnan J Hawsawi¹, Latifa A Jaber¹

¹Department of Clinical Laboratory Sciences, Faculty of Applied Medical Sciences, Umm Al-Qura University, Makkah, Saudi Arabia.

International journal of microbiology

|July 15, 2025

概括

在麦加的献血者查显示,输血传染性感染 (TTIs) 较低. 乙型肝炎标志物很常见,表明先前的暴露,每年变化表明需要持续监测的不断变化的模式.

科学领域:

医学科学医学科学医学科学
公共卫生公共卫生
流行病学流行病学

背景情况:

输血传染病 (TTIs) 对输血安全构成重大风险.
对献血者进行有效的查至关重要,特别是在像沙特阿拉伯麦加城这样的高需求地区.

研究的目的:

在国王阿卜杜拉齐兹医院麦加 (KAHM) 的献血者中评估关键输血传染性感染标志物的血清流行率.
分析7年 (2017-2023) 的TTI流行趋势,并按捐赠者的人口统计数据进行分析.

主要方法:

从2017年1月到2023年12月,对17661次献血的回顾性分析.
血清检测乙型肝炎表面抗原 (HBsAg),乙型肝炎核心抗体 (HBcAb),乙型肝炎表面抗体 (HBsAb),乙型肝炎病毒 (HCV),人类免疫缺陷病毒 (HIV),人类T淋巴细胞病毒 (HTLV-I/II) 和梅毒.
数据按年份,性别,年龄,捐赠者类型和捐赠类别进行分类.

主要成果:

总的来说,TTI的流行率较低:HBsAg (0.42%),HCV (0.29%),HIV (0.06%),HTLV-I/II (0.05%),梅毒 (0.44%) 等.
乙型肝炎标志物的高患病率:HBcAb (8.03%) 和HBsAb (7.33%),表明之前的暴露.
观察到HBsAg,HBcAb和HBsAb的统计学上显著的年度变化 (p < 0.007).

结论:

目前在麦加的献血者查方案有效地保持了低的TTI患病率.
乙型肝炎核心抗体的显著流行突显出需要了解过去的暴露模式.
血清阳性每年的波动需要持续的流行病学监测和有针对性的公共卫生干预措施.

关键词:

沙特阿拉伯沙特阿拉伯沙特阿拉伯献血者献血者献血者献血者献血者输血输血输血输血输血传染病是一种传染性疾病.输血传播的感染输血传播的感染

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