积极的社会建模减轻了nocebo的副作用
Cosette Saunders1, Winston Tan1, David Ng1
1School of Psychology, University of Sydney, Sydney, Australia.
概括
观察积极的治疗经验,称为积极的社会建模,可以显著减少nocebo副作用. 这种干预有助于减轻负面指令和不良经验对健康的负面影响.
科学领域:
- 心理学 心理学 心理学
- 医学研究 医学研究
- 行为科学 行为科学
背景情况:
- 负面的指示和观察不良经验可以通过nocebo效应恶化健康结果.
- 观察积极经验以抵消这些影响的潜力仍然在很大程度上未被探索.
研究的目的:
- 为了确定积极的社会建模是否可以减少nocebo副作用.
- 研究观察积极治疗经验对诱导副作用的影响.
主要方法:
- 160名参与者接受了安慰剂,并接受了副作用警告.
- 组被随机分配,以查看积极的社会建模或不,并遇到现实模型显示副作用或不.
- 症状严重程度被评估为主要的结局指标.
主要成果:
- 证实了显著的nocebo效应,在安慰剂组与自然史组相比,安慰剂组的症状严重程度更高.
- 积极的社会建模明显减少了症状的严重程度.
- 单独的指导和附带副作用建模的指导之间没有发现显著差异.
结论:
- 积极的社会建模有效地减少了nocebo的副作用,不管它们是由单独的指令引起的还是通过观察负面的副作用.
- 这种干预措施有望减轻临床实践中无效疗法效应的负担.
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