用整合酶链转移抑制剂治疗小鼠的胎儿缺陷:多卢特格拉维尔,拉尔特格拉维尔,比克特格拉维尔和卡博特格拉维尔的比较

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...