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Updated: Sep 15, 2025

Time-dependent Increase in the Network Response to the Stimulation of Neuronal Cell Cultures on Micro-electrode Arrays
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Time-dependent Increase in the Network Response to the Stimulation of Neuronal Cell Cultures on Micro-electrode Arrays

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从单细胞数据恢复时间变化的网络

Euxhen Hasanaj1, Barnabás Póczos1, Ziv Bar-Joseph1,2

  • 1Machine Learning Department, Carnegie Mellon University, Pittsburgh, PA 15213, United States.

Bioinformatics (Oxford, England)
|July 15, 2025
PubMed
概括

我们开发了Marlene,这是一个深度学习工具,可以从单细胞数据中重建动态基因调节网络. 这种方法准确地识别了复杂的生物过程中的基因相互作用,如衰老和免疫反应.

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Protein Dynamics in Living Cells01:19

Protein Dynamics in Living Cells

Different fluorescence-based techniques are used to study the protein dynamics in living cells. These techniques include FRAP, FRET, and PET.
Fluorescent recovery after photobleaching (FRAP) is a fluorescent-protein-based detection technique used to quantify protein movement rates within the cell. This method exposes a small portion of the cell to an intense laser beam. The laser beam causes permanent photobleaching of the fluorophore-tagged proteins in the exposed region. As the bleached...
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