多尺度建模如何有助于检查健康的社会决定因素以及由此产生的差异
Kyoko Yoshida1, Elsje Pienaar2, Shalanda A Bynum3
1Department of Biomedical Engineering, University of Minnesota, Minneapolis, Minnesota, United States of America.
PLoS computational biology
|July 15, 2025
概括
健康的社会决定因素 (SDOH) 显著影响人口健康,导致持续的健康差异. 多尺度建模提供了一种有希望的方法,可以更好地理解和解决这些不利的SDOH影响.
科学领域:
- 公共卫生 公共卫生
- 计算生物学 计算生物学
- 健康差距 研究 研究 研究 研究
背景情况:
- 健康的社会决定因素 (SDOH) 涵盖影响日常生活和健康结果的条件.
- 人口之间SDOH的显著变化有助于持续和恶化的健康差异.
- 现有的努力,以表征和减少健康差异面临着持续的挑战.
研究的目的:
- 探索多尺度建模在描述不良SDOH的潜力.
- 综合从机构间建模和分析小组多层次建模会议 (2023年6月28日至29日) 的讨论.
- 发出SDOH和多尺度建模社区之间的跨学科合作呼吁,以改善人口健康.
主要方法:
- 该研究总结和综合了科学会议上专门会议的讨论.
- 它确定了当前SDOH研究中的挑战.
- 它强调了多尺度建模对于应对这些挑战的适用性.
主要成果:
- 多尺度建模为特征不利的SDOH提供了独特的能力.
- 跨学科的合作对于SDOH研究中多尺度建模的成功应用至关重要.
- 确定了促进将多尺度建模整合到SDOH研究中的具体需求.
结论:
- 多尺度建模对于推进SDOH和健康差异研究具有重大潜力.
- 加强跨学科科学对于利用这些建模方法至关重要.
- 未来的研究应该专注于整合多尺度建模,以更好地理解和减轻健康差异.
相关概念视频
Dimensions of Health and Illness
8.3K
The factors influencing the health-illness continuum can be internal or external and may or may not be under conscious control. They are related to the following eight human dimensions, and each dimension is interrelated to one other.
8.3K
Models of Health Promotion and Illness Prevention I
2.2K
A model is a theoretical way to understand a concept or an idea. Models can overcome barriers to health regardless of diverse economic and cultural backgrounds. In addition, models make the task easier by providing different ways to approach complex issues. There are two major health promotion models: the health belief model and the health promotion model.
The health belief model (HBM) attempts to predict health-related behavior in specific belief patterns. According to the HBM, a person's...
The health belief model (HBM) attempts to predict health-related behavior in specific belief patterns. According to the HBM, a person's...
2.2K
Models of Health Promotion and Illness Prevention II
1.7K
The person's health status fluctuates continually, varying from being in good health to becoming ill and returning to being healthy. To understand the concept of illness prevention, there are two models. First, the health-illness continuum model is a graphic representation of an individual's wellness. It states that a person is considered healthy in the absence of physical disease and the presence of good emotional health.
The agent-host-environment model states that disease results...
The agent-host-environment model states that disease results...
1.7K
Strategies for Assessing and Addressing Confounding
159
Confounding is a critical issue in epidemiological studies, often leading to misleading conclusions about associations between exposures and outcomes. It occurs when the relationship between the exposure and the outcome is mixed with the effects of other factors that influence the outcome. Given that, addressing confounding is of high importance for drawing accurate inferences in research.
Confounding can be addressed at both the design phase of a study and through analytical methods after data...
Confounding can be addressed at both the design phase of a study and through analytical methods after data...
159
Mechanistic Models: Compartment Models in Individual and Population Analysis
87
Mechanistic models are utilized in individual analysis using single-source data, but imperfections arise due to data collection errors, preventing perfect prediction of observed data. The mathematical equation involves known values (Xi), observed concentrations (Ci), measurement errors (εi), model parameters (ϕj), and the related function (ƒi) for i number of values. Different least-squares metrics quantify differences between predicted and observed values. The ordinary least...
87
Concepts of Health and Illness
15.5K
Health is a condition of the body, mind, and spirit where an individual remains free from illness. Similarly, wellness is an active state, including living a lifestyle that promotes physical, mental, and emotional health. Physical health is critical for the overall well-being and can be affected by lifestyle, activity level, diet, and behavior. The highest attainable standard of health is a fundamental and universal human right. Consider Lisa, a fifteen-year-old born with congenital...
15.5K


