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维护血液透析患者的跌倒风险:对HOPE联盟试验的二次分析
David M Charytan1, Alvin H Moss2,3, Manar Shalak3
1Division of Nephrology, Department of Medicine, New York University Grossman School of Medicine, New York, NY.
概括
在血液透析患者中,跌倒很常见,28%的患者在36周内经历了跌倒. 大多数跌倒发生在家中由于意外,而不是在透析治疗期间.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 老年病的医生 老年病的医生
- 公共卫生 公共卫生
背景情况:
- 对于接受维护血液透析的患者来说,跌倒是一个重大问题.
- 关于这群脆弱人群中跌倒的频率,情况和结果的数据有限.
研究的目的:
- 调查维护血液透析患者中跌倒的发生率,时间,原因和结果.
- 为了确定与此患者群体中跌倒相关的风险因素.
主要方法:
- 在HOPE联盟试验 (NCT04571619) 中进行的前性研究,涉及643名成年血液透析患者.
- 在36周的时间内监测下降,每隔四周收集数据.
- 使用多变量回归分析来探索患者特征与跌倒风险之间的关联.
主要成果:
- 178名参与者 (28%) 在429个参与者年中经历了293次跌倒,每参与者年跌倒率为0.68.
- 事故是最常见的原因 (38%),在透析单元中很少发生跌倒.
- 14%的跌倒导致住院治疗,7%导致骨折;症状或药物使用与跌倒风险之间没有发现联系.
结论:
- 在维护血液透析患者中,特别是在慢性疼痛患者中,跌倒是常见的.
- 大多数跌倒发生在家庭环境中,并且是意外的.
- 患者报告的症状和药物使用并不是该队列中跌倒风险的显著预测因素.
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