语音延迟渐进性失言症:一种与初级渐进性失言症不同的新型临床实体 - 一个描述性的案例系列
Shun Akaike1, Shigehisa Ura2, Akihiko Ogata3
1Department of Neurology, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido, Japan.
语音延迟渐进性失语症 (DPAOS) 是一种独特的神经退行性疾病,具有轻微的,孤立的语音障碍. 它不同于初级渐进性失言症 (PPA),其发病时间较晚,症状不那么严重.
科学领域:
- 神经科学是一个神经科学.
- 神经学 神经学
- 语音语言病理学 语言病理学
背景情况:
- 初级渐进性失言症 (PPA) 是一种神经退行性综合征,语言障碍是主要的早期症状.
- 神经退行性疾病的一个子集呈现出以后出现的语音语言障碍,称为延迟渐进性失言症 (DPA).
- 语音延迟渐进性失言症 (DPAOS) 在DPA中被定义为没有失言症的孤立失言症 (AOS).
研究的目的:
- 介绍和定义延迟渐进性失言症 (DPA) 和语音延迟渐进性失言症 (DPAOS).
- 为了比较临床表现和语音语言障碍的严重程度在DPAOS与非流利/语法PPA (naPPA).
主要方法:
- 对神经退行性疾病患者延迟言语语言障碍的回顾性审查.
- 六名DPAOS患者与11名naPPA患者的疾病持续时间匹配的比较.
- 使用贝叶斯线性回归分析评估的神经心理性能.
主要成果:
- 所有六名DPA患者都分离了AOS而没有失言症,形成了DPAOS组.
- 与naPPA患者相比,DPAOS患者的AOS明显较轻.
- naPPA患者往往表现出更严重的AOS,书法主义或贫血症.
结论:
- DPAOS是渐进性AOS的一个明显的临床表现,晚些时候出现并保持更温和和更孤立.
- DPAOS和naPPA在临床过程和严重程度上有所不同,尽管潜在的病理重叠.
- 识别DPAOS可能有助于早期检测神经退行性疾病中的渐进性语言障碍.
更多相关视频
10:15Utilizing Repetitive Transcranial Magnetic Stimulation to Improve Language Function in Stroke Patients with Chronic Non-fluent Aphasia
Published on: July 2, 2013
08:16Utility of Dissociated Intrinsic Hand Muscle Atrophy in the Diagnosis of Amyotrophic Lateral Sclerosis
Published on: March 4, 2014
相关概念视频
Parkinson's Disease: Overview
Autism Spectrum Disorder
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
Higher Mental Functions of the Brain: Language
Language formation and comprehension take place in the dominant hemisphere. The dominant hemisphere is responsible for understanding the meaning of spoken, written, or sign language, as well as the ability to communicate. For most people, the left hemisphere is the dominant one. The right hemisphere, then, gives tone and emotional context to the...
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
Alzheimer's Disease: Overview
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
Peripheral Artery Disease I: Introduction
