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基于细胞和细胞组件的微/纳米电机
Kaige Zheng1, Lingke Li1, Qian Li1
1School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China; Henan Key Laboratory of Targeting Therapy and Diagnosis for Critical Diseases, Zhengzhou 450001, China; Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education, Zhengzhou 450001, China.
Acta biomaterialia
|July 15, 2025
概括
细胞微/纳米电机 (MNM) 利用纳米技术用于先进的生物医学应用. 这些生物相容电机提供了改进的药物输送和成像,克服了传统的局限性.
科学领域:
- 生物医学工程 生物医学工程
- 纳米技术 纳米技术
- 材料科学 材料科学 材料科学
背景情况:
- 微/纳米发动机 (MNM) 是一个快速发展的纳米技术领域,具有重要的生物医学潜力.
- 传统的药物递送方法在向和生物可用性方面面临挑战,但MNM可以克服这些挑战.
- 基于细胞或细胞组件的纳米电机与其他材料相比,具有更高的生物相容性和生物降解性.
研究的目的:
- 审查基于细胞/细胞组件的微/纳米电机的制备方法和应用.
- 突出这些生物基纳米电机在生物医学领域的优势.
- 讨论这个新兴技术的现状,挑战和未来前景.
主要方法:
- 系统审查最近 (过去三年) 细胞和生物微纳米电机的进展.
- 专注于核心优势和应用,特别是精确的药物输送和多功能集成.
- 分析关键问题,挑战和未来的研究方向.
主要成果:
- 细胞微/纳米发动机在向药物输送,物质输送和成像方面具有显著的潜力.
- 这些生物启发的电机将细胞生物相容性与纳米电机的精确控制相结合.
- 最近的进展突出了它们在制造人工细胞和微型机器人的作用.
结论:
- 基于细胞和细胞组件的微纳米发动机代表了纳米技术和生物医学交叉处的一个有希望的前沿.
- 需要进一步的研究来应对当前的挑战,并充分发挥其在临床应用中的潜力.
- 本综述为设计和制造用于生物医学应用的先进生物基微型/纳米电机提供了见解.
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