具有激活ZKSCAN1::MET激酶融合的先天性斯皮茨黑色细胞瘤
Tzah Feldman1, Hiba Zaaroura2, Hanaa Haj Abaya2
1Department of Pathology, Rambam Health Care Campus, Haifa, Israel.
Journal of cutaneous pathology
|July 15, 2025
概括
先天性斯皮茨瘤很罕见,通常通过组织学诊断. 分子分析显示,ZKSCAN1::MET融合在先天的斯皮茨瘤中,突出了基因测试对于准确诊断的重要性.
科学领域:
- 皮肤病学 皮肤病学
- 在瘤学瘤学.
- 分子病理学分子病理学
背景情况:
- 先天性斯皮茨瘤很少被记录下来,诊断依赖于组织病理学和免疫组织化学.
- 斯皮茨瘤代表了一种具有可变恶性潜力的黑色素细胞瘤的谱.
关键词:
斯皮茨是什么意思 斯皮茨是什么意思ZKSCAN1::METSCAN1::METSCAN1::METSCAN1::METSCAN1::METSCAN1::METSCAN1::METSCAN1::METSCAN1::METSCAN1::METSCAN1::METSCAN1::METSCAN1::METSCAN1::METSCAN1::METSCAN1::METSCAN1::METSCAN1::METSCAN1::METSCAN1::METSCAN1::METSCAN1::METSCAN2::METSCAN2::METSCAN3::METSCAN4::METSCAN4这是先天的,先天的.黑色细胞瘤 (Melanocytoma) 是一种细胞瘤.
相关概念视频
01:20The Retinoblastoma Gene
4.2K
Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
4.2K
02:23Abnormal Proliferation
4.6K
Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the...
4.6K