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Updated: May 13, 2026

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通过EWSR1::FLI1颠覆mRNA降解途径代表了Ewing肉瘤的治疗脆弱性

Bartimée Galvan1,2, Loïc Ongena1, Jonathan Bruyr1

  • 1Laboratory of Gene Expression and Cancer, GIGA Institute, University of Liège (ULiège), Liège, Belgium.

Nature communications
|July 15, 2025
PubMed
概括

EWSR1::FLI1,在尤宁肉瘤中的转录因子,也通过加速mRNA衰变促进癌症. 这种新发现的功能使得癌细胞容易受到针对HuR的治疗.

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