[在跨导管大动脉更换过程中使用脑栓塞保护装置的经验]
Lan Zhang1,2, Xinmin Liu3, Ziwei Xi4
1Center for Valvular Heart Disease Intervention, Beijing Anzhen Hospital, Capital Medical University, National Clinical Research Center for Cardiovascular Diseases, Beijing 100029, China. zhanglan0621@sina.com.
概括
哨兵脑栓塞保护装置 (CEPD) 在跨导管大动脉置换 (TAVR) 期间是可行的和安全的,在92.5%的患者中捕获碎片. 这项研究证实了它在各种主动脉门类型中的有效性.
科学领域:
- 心血管医学 心血管医学
- 干预心脏病学 干预心脏病学
- 生物医学工程 生物医学工程
背景情况:
- 过导管大动脉置换 (TAVR) 是对大动脉狭窄的日益增长的手术.
- 在TAVR期间的大脑栓塞保护旨在降低中风风险.
- 哨兵脑栓塞保护装置 (CEPD) 旨在在TAVR过程中捕获碎片.
研究的目的:
- 在TAVR期间评估Sentinel CEPD的可行性,有效性和安全性.
- 为了评估不同类型的大动脉的Sentinel CEPD性能.
- 分析中风,过渡性缺血性发作和其他与Sentinel CEPD在TAVR中的使用相关的并发症的发生率.
主要方法:
- 对80名接受Sentinel CEPDTAVR治疗的患者进行了回顾性分析.
- 从2023年10月到2024年9月收集的数据.
- 主要终点包括Sentinel CEPD植入成功,全因死亡率,中风,TIA和30天内进入血管并发症.
主要成果:
- 在98.8%的患者中,Sentinel CEPD植入成功.
- 在92.5%的案例中捕获了宏观可见的碎片.
- 没有观察到有症状的中风或全因死亡率;发生了一次过渡性缺血性发作. 没有接入容器并发症.
结论:
- 哨兵CEPD显示TAVR在各种大动脉门类型中具有高可行性和安全性.
- 该设备在捕获栓塞物质方面显示出潜在的有效性.
- 在TAVR中使用Sentinel CEPD与神经事件和血管并发症的风险较低有关.
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