图像 1927 nm 分数图激光 - 组织相互作用: 一种非吸收到吸收效应的光谱
Emily Wenande1, Kevin Jacobsen1, Gabriela Lladó Grove1
1Department of Dermatology, Copenhagen University Hospital - Bispebjerg and Frederiksberg, Copenhagen, Denmark.
Journal of cosmetic dermatology
|July 16, 2025
概括
1927nm分数纤维激光器 (FTL) 在人体皮肤中提供可调节的非消耗效应到消耗效应. 不同的脉冲能量和激光尖端大小允许精确控制微热处理区深度和形态.
科学领域:
- 皮肤病学 皮肤病学
- 激光物理 激光物理
- 生物医学成像技术 生物医学成像技术
背景情况:
- 针对组织水的微分红外激光被分类为非消耗性或消耗性.
- 1927纳米的分数纤维激光器 (FTL) 具有中间的吸水系数,这表明可能存在一系列效应.
研究的目的:
- 为了研究1927nm FTL和体内人体皮肤之间的动态相互作用.
- 探索不同脉冲能量如何影响FTL组织效应,使用光学相干断层扫描 (OCT) 和线场相聚焦 OCT (LC-OCT).
主要方法:
- 对前臂皮肤进行了FTL暴露,脉冲能量为0,3,15或20mJ.
- 在20瓦功率下使用了两种不同点大小的激光尖端 (200微米 (C1) 和350微米 (C5)).
- 在治疗后立即使用OCT和LC-OCT成像来评估微热处理区 (MTZ) 形态,直径和切除深度.
主要成果:
- 随着脉冲能量和激光尖端,FTL诱导的MTZ形态发生了显著的变化,从非除性表皮效应到除性皮肤效应.
- 较低的脉冲能量 (3mJ) 主要影响表皮,产生亚表皮裂或表皮破坏.
- 较高的脉冲能量 (15-20mJ) 增加了MTZ宽度和移除深度进入表面皮肤,与更明显的角层参与.
结论:
- FTL-组织相互作用具有高度可控性,并且可以在非消耗性到消耗性频谱中进行调制.
- 脉冲能量和激光尖端选择是定制FTL治疗结果的关键参数.
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