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Updated: Sep 15, 2025

Development and Maintenance of a Preclinical Patient Derived Tumor Xenograft Model for the Investigation of Novel Anti-Cancer Therapies
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Development and Maintenance of a Preclinical Patient Derived Tumor Xenograft Model for the Investigation of Novel Anti-Cancer Therapies

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新的高度强大的c-Met降解剂对抗广泛的癌症

Changkai Jia1,2, Pengli Wei1,3, Shiyang Sun1,2

  • 1National Engineering Research Center for Strategic Drugs, Beijing Institute of Pharmacology and Toxicology, Beijing 100850, China.

Journal of medicinal chemistry
|July 16, 2025
PubMed
概括

新的c-Met降解剂D19和G4在MET驱动的癌症中克服了耐药性. 口服D19和G4完全抑制异种移植瘤,并与其他抑制剂产生协同作用.

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