美国阿斯伯吉洛症诊断的流行病学使用国家EHR数据库,2013-2023年
Brittany L Morgan Bustamante1, Elijah G Martinez1, Aidan Lee2
1Division of Environmental Health Sciences, University of California, Berkeley, Berkeley, CA 94720.
medRxiv : the preprint server for health sciences
|July 16, 2025
概括
在美国,从2013年到2023年,阿斯伯吉洛症的患病率每年上升5%,因COVID-19而加剧了这种差异. 该研究强调男性,老年人和城市人口的风险增加,对少数群体和农村居民的新兴担忧.
科学领域:
- 流行病学 流行病学
- 传染性疾病 传染性疾病
- 公共卫生监督 公共卫生监督
背景情况:
- 阿斯伯吉洛症是一种未被认可的真菌感染,在美国具有显著的发病率和死亡率.
- 碎片化的国家数据阻碍了对阿斯珀吉洛斯病趋势的全面理解和监测.
- 住院病例的增加和抗真菌耐药性的增加强调了更新流行数据的必要性.
研究的目的:
- 分析美国阿斯伯吉洛症流行 (2013-2023) 的人口,地理和时间趋势.
- 评估COVID-19大流行对不同人口子群体中阿斯伯吉洛症患病率的影响.
- 根据患者的特征和位置,识别阿斯伯吉洛症患病率的差异.
主要方法:
- 使用大型的国家电子健康记录 (EHR) 数据库进行回顾性队列研究.
- 包括来自美国142个医疗保健系统的7600多万成年患者 (2013-2023年).
- 使用准森和贝叶斯空间时间回归分析流行率,以COVID-19作为时间变化的暴露.
主要成果:
- 阿斯伯吉洛症的患病率每年增加5%,在2022年达到顶峰,具有显著的地理差异.
- 在男性,老年人 (≥65岁) 和城市居民中观察到更高的患病率.
- 在COVID-19后,西班牙裔/拉丁裔患者,种族少数群体中患病率不成比例地增加,并在农村居民中显示出新兴趋势.
结论:
- 这项研究提供了对阿斯珀吉洛斯病模式的最全面的国家评估,揭示了患病率上升和大流行驱动的差异.
- 临床医生应考虑区域和人口风险因素,以提前诊断和改善结果,特别是对于弱势群体.
- 加强诊断资源和意识对于服务不足的地区和经历风险概况转变的人群至关重要.
相关概念视频
Prevalence and Incidence
825
In statistical epidemiology and health sciences, two essential metrics—prevalence and incidence—are fundamental for understanding disease dynamics within a population. These measures enable public health officials, epidemiologists, and researchers to assess the burden of diseases, allocate resources effectively, and design impactful public health policies and interventions.
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
825
Fungal Phylum Ascomycota
159
Phylum Ascomycota, a major division within the subkingdom Dikarya, comprises a diverse range of fungal species, including both unicellular yeasts and filamentous molds such as Aspergillus and Penicillium. These fungi thrive in a variety of habitats, from aquatic ecosystems to terrestrial environments, playing crucial ecological and economic roles.Morphology and ReproductionThe defining characteristic of Ascomycetes, commonly referred to as sac fungi, is the ascus—a sac-like structure that...
159
Asthma-IV: Diagnostic and Management
2.6K
The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
2.6K
Steps in Outbreak Investigation
209
In the ever-evolving field of public health, statistical analysis serves as a cornerstone for understanding and managing disease outbreaks. By leveraging various statistical tools, health professionals can predict potential outbreaks, analyze ongoing situations, and devise effective responses to mitigate impact. For that to happen, there are a few possible stages of the analysis:
209
Enzyme-Linked Immunosorbent Assay
14.2K
In 1971, Peter Perlman and Eva Engvall developed an Enzyme-linked immunosorbent assay (ELISA or EIA). ELISA differs from western blot in that the assays are conducted in microtiter plates or in vivo rather than on an absorbent membrane.
There are many different types of ELISAs, but they all involve an antibody molecule whose constant region binds an enzyme, leaving the variable region free to bind its specific antigen. Enzyme-substrate reaction allows the antigen to be visualized or...
There are many different types of ELISAs, but they all involve an antibody molecule whose constant region binds an enzyme, leaving the variable region free to bind its specific antigen. Enzyme-substrate reaction allows the antigen to be visualized or...
14.2K
Documentation of Nursing Diagnosis
1.3K
The nurse documents nursing diagnoses and enters them into the patient record. The identified patient's nursing diagnosis is either written out with a plan of care or entered into the electronic health record.
In some settings, data-driven computerized decision support systems are in place, allowing for more accurate nursing diagnoses. The database within one of these systems includes diagnostic labels defining characteristics, activities, and indicators for nursing. A nurse enters...
In some settings, data-driven computerized decision support systems are in place, allowing for more accurate nursing diagnoses. The database within one of these systems includes diagnostic labels defining characteristics, activities, and indicators for nursing. A nurse enters...
1.3K


