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阿克里顿产药具有增强的双阶段抗疟疾疗效

Rozalia A Dodean1,2, Yuexin Li2, Xiaowei Zhang2

  • 1Department of Chemistry, Portland State University, Portland, Oregon 97201, United States.

ACS medicinal chemistry letters
|July 16, 2025
PubMed
概括

一种新的前药物策略产生了强大的双阶段抗疟疾药物阿克里类型. 与其原始化合物T226相比,T235前药在感染疟疾的小鼠中显示出优异的口服疗效和激进治疗潜力.

关键词:
亚克里多尼斯 亚克里多尼斯这是一种抗疟疾药物.这是一种抗plasmodial.血液阶段 - 血液阶段它是双阶段的双阶段.肝脏阶段 - 肝脏阶段疟疾 疟疾 是一种疾病.作为一种前药物,它是一种前药物.预防性 预防性彻底治愈 彻底治疗 彻底治疗

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