手术前的黑激素对患有发酵性白内障手术的患者的焦虑和疼痛的影响
N Sarala1, K Bhuvana1, T Sangeetha2
1Department of Pharmacology, Sri Devaraj Urs Medical College, Sri Devaraj Urs Academy of Higher Education and Research, Kolar, Karnataka, India.
Oman journal of ophthalmology
|July 16, 2025
概括
与白内障手术患者相比,黑素显著降低了手术前的焦虑和镇静,而黑相比,减少了白内障手术患者的镇静. 这项研究强调了黑激素作为一种潜在的优越选择,用于在发酵过程中管理患者的焦虑.
科学领域:
- 眼科医生 眼科 眼科
- 麻醉学 麻醉学
- 药理学 药理学是指药理学的学科.
背景情况:
- 手术前的焦虑是常见的,在患者接受的法化白内障手术.
- 二类药物通常用于控制这种焦虑.
- 黑素的抗焦虑和止痛特性需要作为替代品进行研究.
研究的目的:
- 为了比较黑激素与泽在缓解手术前焦虑症方面的疗效.
- 评估黑激素对疼痛,镇静和眼内压力的影响.
- 评估患者的合作和手术期间的情况.
主要方法:
- 199名患者被随机分配,在手术前90分钟口服3毫克黑激素或5毫克亚泽帕.
- 在多个时间点记录了焦虑 (VAS),疼痛 (VPS) 和镇静得分.
- 眼内压力 (IOP) 和手术内条件也被评估.
主要成果:
- 与迪亚泽巴姆相比,黑素显著降低了焦虑和镇静评分 (P=0.0001).
- 两组之间没有观察到疼痛得分或眼内压力的显著差异.
- 在手术期间的病情在71%的黑激素患者中被评为优秀,而在28%的糖尿病患者中是如此.
结论:
- 黑素在减少手术前的焦虑和白内障手术期间的镇静方面比迪亚泽巴姆更有效.
- 黑色素改善了患者在手术期间的合作.
- 黑素在发酵乳化中为焦虑管理提供了一个有希望的替代方案.
相关概念视频
Management of Insomnia
324
The sleep cycle, an integral part of human health, consists of several stages with distinct characteristics and functions. It begins with a transition from wakefulness to sleep, known as the light sleep phase, followed by the restorative deep sleep phase, essential for physical recovery and growth. The cycle concludes with the Rapid Eye Movement (REM) phase, characterized by high brain activity and vivid dreaming. Insomnia, a prevalent sleep disorder, involves difficulty falling asleep, staying...
324
Sedatives and Hypnotics Drugs: Miscellaneous Agents
245
Sedatives and hypnotics encompass a wide range of substances, each with its unique mechanism of action, uses, and potential adverse effects.
Melatonin congeners like ramelteon (Rozerem) and tasimelteon (Hetlioz) selectively bind to melatonin receptors (MT1 and MT2) and thus mimic the actions of melatonin, a hormone that regulates sleep-wake cycles. Tasimelteon is primarily used for non-24-hour sleep-wake disorder, common in blind patients. They are also used to treat conditions like insomnia...
Melatonin congeners like ramelteon (Rozerem) and tasimelteon (Hetlioz) selectively bind to melatonin receptors (MT1 and MT2) and thus mimic the actions of melatonin, a hormone that regulates sleep-wake cycles. Tasimelteon is primarily used for non-24-hour sleep-wake disorder, common in blind patients. They are also used to treat conditions like insomnia...
245
General Anesthesia: Overview
286
Anesthesia is a medical procedure that uses drugs for CNS suppression to enable painless surgeries and procedures. The selection of anesthetics is influenced by their pharmacokinetic properties, side effects, and patient characteristics. Various types of anesthesia include general, local, regional, spinal, and inhalational.
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
286
Cardiomyopathy VII: Pre and Post Operative Nursing Management
29
Patients with hypertrophic cardiomyopathy (HCM) and left ventricular outflow tract (LVOT) obstruction who remain symptomatic despite optimal medical therapy may undergo a septal myectomy (Morrow procedure). This procedure involves excising a portion of the hypertrophied septum below the aortic valve using a heart-lung machine to improve blood flow through the LVOT. Effective preoperative and postoperative nursing management ensures successful patient outcomes, minimizes complications, and...
29
Stages of General Anesthesia
724
Various sedation levels offer significant advantages in facilitating procedural interventions for patients undergoing medical or invasive surgical procedures. These levels span from anxiolysis to general anesthesia, providing a spectrum of sedative effects to cater to specific patient needs. Anxiolysis reduces anxiety and is achieved through minimal sedation, enabling patients to remain awake and responsive while feeling more at ease during the procedure. This level can benefit minor...
724
Sedatives and Hypnotics: Overview
662
Sedatives are drugs that alleviate anxiety, while hypnotics induce sleep. Both classes of medication suppress neuronal activity, leading to a calming effect for sedatives and facilitating sleep for hypnotics.
Sedative-hypnotics are categorized into barbiturates, benzodiazepines (BZDs), and non-benzodiazepines or Z-drugs. These drugs work by suppressing central nervous system activity, and this suppression is dose-dependent. Older sedative medications, like barbiturates, follow a linear curve in...
Sedative-hypnotics are categorized into barbiturates, benzodiazepines (BZDs), and non-benzodiazepines or Z-drugs. These drugs work by suppressing central nervous system activity, and this suppression is dose-dependent. Older sedative medications, like barbiturates, follow a linear curve in...
662


