Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Generation of Straight or Branched Actin Filaments01:14

Generation of Straight or Branched Actin Filaments

2.9K
The straight or branched structure formation of actin filaments is controlled by nucleating proteins such as the formins and Arp2/3 complex. Formin-mediated assembly results in straight filaments, whereas Arp2/3 protein complex-mediated assembly results in branched actin filaments.
Arp2/3 Complex
Arp2/3 complex is a seven-subunit complex consisting of two proteins similar to actin- Arp2 and Arp3, and five other subunits that help keep Arp2 and Arp3 inactive. When required, the complex is...
2.9K
The Contractile Ring02:15

The Contractile Ring

6.1K
Contractile rings are composed of microfilaments and are responsible for separating the daughter cells during cytokinesis. Contractile ring assembly proceeds along with other cell cycle events; however, very few mechanistic details are known about the timing and coordination of the contractile rings with the cell cycle.
A small GTPase, RhoA, controls the function and assembly of the contractile ring. RhoA belongs to the Ras superfamily of proteins. The activation of formins by RhoA promotes...
6.1K
Problem-Solving: Tuning of a Guitar String01:04

Problem-Solving: Tuning of a Guitar String

1.2K
In the case of stringed instruments like the guitar, the elastic property that determines the speed of the sound produced is its linear mass density or the mass per unit length. This is simply called the linear density. If the string's linear density is constant along the string, then the linear density is simply the total mass divided by the total length.
The string's wave speed can be regulated by varying the linear density. Tension is the other property that determines the speed of...
1.2K
Statically Indeterminate Problem Solving01:16

Statically Indeterminate Problem Solving

948
Statically indeterminate problems are those where statics alone can not determine the internal forces or reactions. Consider a structure comprising two cylindrical rods made of steel and brass. These rods are joined at point B and restrained by rigid supports at points A and C. Now, the reactions at points A and C and the deflection at point B are to be determined. This rod structure is classified as statically indeterminate as the structure has more supports than are necessary for maintaining...
948

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

3D ECM-inflammation model on a microfluidic chip for neutrophil transmigration from whole blood investigations.

Lab on a chip·2026
Same author

Glymphatic System Dysregulation as a Key Contributor to Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.

International journal of molecular sciences·2025
Same author

On the physiological processes underlying optoretinography [Invited].

Biomedical optics express·2025
Same author

Virus Genome Sequences in the Blood of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients.

medRxiv : the preprint server for health sciences·2025
Same author

Dynamic and precise electromagnetic levitation of single cells.

Proceedings of the National Academy of Sciences of the United States of America·2025
Same author

Patient-reported treatment outcomes in ME/CFS and long COVID.

Proceedings of the National Academy of Sciences of the United States of America·2025
Same journal

Layered social competition coordinates reproductive hierarchy formation in ants.

bioRxiv : the preprint server for biology·2026
Same journal

Combination epigenetic-targeted therapy increases the immunogenicity of poorly immunogenic sarcomas.

bioRxiv : the preprint server for biology·2026
Same journal

Loss of LanC-like proteins delays post-injury regeneration of aging skeletal muscles.

bioRxiv : the preprint server for biology·2026
Same journal

Integrative Transfer Network: Deep Transfer Learning Across Populations and Prediction Targets.

bioRxiv : the preprint server for biology·2026
Same journal

Confidence-supported label-free metabolic imaging with FPhaS phase autofluorescence microscopy.

bioRxiv : the preprint server for biology·2026
Same journal

Sequence-encoded autoinhibition couples mRNA decapping activity to phase separation.

bioRxiv : the preprint server for biology·2026
查看所有相关文章

相关实验视频

Updated: May 4, 2026

Multi-step Variable Height Photolithography for Valved Multilayer Microfluidic Devices
10:18

Multi-step Variable Height Photolithography for Valved Multilayer Microfluidic Devices

Published on: January 27, 2017

14.5K

轻管弦的多阶段固相小滴子反应堆.

Mo Wu, Mohammad A Zaman, Michael A Jensen

    bioRxiv : the preprint server for biology
    |July 16, 2025
    PubMed
    概括
    此摘要是机器生成的。

    这项研究引入了一种新型的光控制的小滴子反应器,用于复杂的生物化学反应. 该平台可实现高精度的多步合成和分析,使用最小的试剂.

    更多相关视频

    A Femtoliter Droplet Array for Massively Parallel Protein Synthesis from Single DNA Molecules
    10:45

    A Femtoliter Droplet Array for Massively Parallel Protein Synthesis from Single DNA Molecules

    Published on: June 20, 2020

    10.4K
    Optimization of Radiochemical Reactions using Droplet Arrays
    10:54

    Optimization of Radiochemical Reactions using Droplet Arrays

    Published on: February 12, 2021

    3.5K

    相关实验视频

    Last Updated: May 4, 2026

    Multi-step Variable Height Photolithography for Valved Multilayer Microfluidic Devices
    10:18

    Multi-step Variable Height Photolithography for Valved Multilayer Microfluidic Devices

    Published on: January 27, 2017

    14.5K
    A Femtoliter Droplet Array for Massively Parallel Protein Synthesis from Single DNA Molecules
    10:45

    A Femtoliter Droplet Array for Massively Parallel Protein Synthesis from Single DNA Molecules

    Published on: June 20, 2020

    10.4K
    Optimization of Radiochemical Reactions using Droplet Arrays
    10:54

    Optimization of Radiochemical Reactions using Droplet Arrays

    Published on: February 12, 2021

    3.5K

    科学领域:

    • 生物化学 生物化学
    • 微流体学 微流体学
    • 合成生物学 合成生物学

    背景情况:

    • 皮科升滴滴微流体提供高效率,但仅限于单步反应.
    • 目前的平台缺乏试剂交换和洗的能力,阻碍了复杂的多步骤过程.
    • 执行多步骤的过程,如寡核酸合成和免疫试验,需要先进的滴滴操纵.

    研究的目的:

    • 开发一种新的平台,克服当前用于多步反应的点滴微流体的局限性.
    • 为了实现精确的连续操作滴和微粒复杂的化学合成.
    • 为了展示一个用于微型化,自动化试剂处理的多功能系统.

    主要方法:

    • 开发光编排的固相小滴子反应器.
    • 使用光电子 tweezers 进行个人 picodroplet 和微珠操纵.
    • 一个以点击化学为基础的八步循环DNA结合合成循环的演示,在现场检测.

    主要成果:

    • 通过使用不同的试剂滴来实现精确的连续封装和解封珠.
    • 确保均的试剂暴露和有效的洗,减轻传统方法的错误.
    • 成功执行了八步DNA结合合成与实时光检测.

    结论:

    • 开发的平台克服了皮科滴滴微流体的单步限制.
    • 它可以精确控制多步骤反应,减少错误和试剂消耗.
    • 该系统显示了可扩展,自动化试剂处理在合成生物学和药物发现中的潜力.