人类群体为外部和内部驱动的任务需求启动网络
bioRxiv : the preprint server for biology
|July 16, 2025
概括
关闭层,一个大脑区域,通过激活任务依赖的大脑网络,启动用于认知控制的网络状态. 这种皮层下核在工作记忆和自传记忆等任务期间的认知功能中起着关键作用.
科学领域:
- 神经科学是一个神经科学.
- 认知神经科学 认知神经科学
- 系统神经科学 系统神经科学
背景情况:
- 认知控制依赖于多个大脑网络中的动态相互作用,受任务需求的影响.
- 这些网络的功能障碍与神经精神疾病有关,但潜在的神经机制仍然不清楚.
研究的目的:
- 调查关闭空间在激活认知控制的任务依赖网络状态中的作用.
- 在工作和自传记忆任务期间,确定闭馆是否影响认知控制网络.
主要方法:
- 功能性磁共振成像 (fMRI) 用于在工作记忆过程中测量420名参与者的大脑活动,并在自传记忆任务中测量35名参与者的大脑活动.
- 进行了结构连接和有效连接分析,以检查关闭空间对认知控制网络的影响.
主要成果:
- 在这两项记忆任务中,闭关体对任务相关的认知控制网络节点的活性增加和激发性影响增加.
- 与前面的insula和pulvinar相比,claustrum表现出更强的激发性有效连接性和更大的结构连接性与与任务相关的网络节点.
结论:
- 关闭层在启动认知控制所必需的网络状态方面发挥着至关重要的作用.
- 这些发现确定了关闭层作为一个关键的皮下细胞核,参与编排认知任务期间的大脑网络活动.
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