在Tet2缺陷CHIP中通过XPO1抑制和Atf3恢复减少炎症和动脉样硬化

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Updated: Sep 15, 2025

Quantitative Analysis of Cellular Composition in Advanced Atherosclerotic Lesions of Smooth Muscle Cell Lineage-Tracing Mice
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Quantitative Analysis of Cellular Composition in Advanced Atherosclerotic Lesions of Smooth Muscle Cell Lineage-Tracing Mice

Published on: February 20, 2019

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Nicole Prutsch, Amélie Vromman, Brittaney Leeper

    bioRxiv : the preprint server for biology
    |July 16, 2025
    PubMed
    概括

    克隆性血液形成中的TET2突变驱动炎症和心血管疾病. 药物ELTANEXOR通过恢复ATF3结合来减少动脉样硬化斑块,提供了一个新的治疗策略.

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